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Innovations in Health Literacy Research - Board On Population Health And Public Health Practice - Bog - National Academies Press - Plusbog.dk

Barriers, Challenges, and Supports for Family Caregivers in Science, Engineering, and Medicine - Engineering Committee On Policies And Practices For

Barriers, Challenges, and Supports for Family Caregivers in Science, Engineering, and Medicine - Engineering Committee On Policies And Practices For

Before the COVID-19 pandemic, research demonstrated a significant impact of family caregiving responsibilities on the careers of professionals who work in science, technology, engineering, mathematics, and medicine (STEMM) - especially women. The COVID-19 pandemic increased public recognition of the challenges experienced by caregivers in STEMM fields and created a sense of urgency among many stakeholders. As part of the information-gathering stage of a forthcoming consensus study to address the barriers faced by caregivers, of all genders, in STEMM fields, the Committee on Policies and Practices for Supporting Family Caregivers Working in Science, Engineering, and Medicine organized two national symposia on February 27 and March 27, 2023. Scholars and leaders from a range of sectors convened to identify evidence-based interventions that can support the recruitment, retention, and advancement of caregivers in science, engineering, and medical fields. This publication summarizes the presentations and discussion of the symposia. Table of ContentsFront Matter1 Introduction2 Outlining the Challenges Facing Caregivers in STEMM3 Understanding the Federal and State Policy Landscape4 Organizational Policies Supporting Caregivers in STEMM5 Research on Different Types of Caregivers6 Federal Responses to Address CaregivingReferencesAppendix A: Public Meeting AgendasAppendix B: Biographical Sketches of Planning Committee Members and Speakers

DKK 182.00
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Innovations in Service Delivery in the Age of Genomics - Board On Health Sciences Policy - Bog - National Academies Press - Plusbog.dk

Intelligent Sustainment and Renewal of Department of Energy Facilities and Infrastructure - Committee On The Renewal Of Department Of Energy

Reducing Inequalities Between Lesbian, Gay, Bisexual, Transgender, and Queer Adolescents and Cisgender, Heterosexual Adolescents - Division Of

Violence and Mental Health - Board On Global Health - Bog - National Academies Press - Plusbog.dk

Priorities on the Health Horizon - National Academy Of Medicine - Bog - National Academies Press - Plusbog.dk

Priorities on the Health Horizon - National Academy Of Medicine - Bog - National Academies Press - Plusbog.dk

In response to a growing national awareness that the development and use of new diagnostic, therapeutic, and preventive interventions had been occurring at a quickening pace—one far outstripping the evidence necessary to make informed decisions about their comparative advantage—the Patient-Centered Outcomes Research Institute (PCORI) was established in 2010 as part of the Affordable Care Act legislation. PCORI is guided by the imperative to help patients, families, clinicians, and other health care stakeholders make better informed health care decisions and improve care and outcomes. To inform the next steps in its organizational strategy, PCORI enlisted the National Academy of Medicine (NAM) to leverage its deep experience in convening experts on matters of significant national importance, including its long-standing thought leadership role in the realization of a learning health system. The NAM formed a multi-stakeholder workgroup and held two virtual convenings with the objective of engaging with patients, clinicians, health system leaders, researchers, and other stakeholders from the broader health community to identify and discuss high-priority emerging issues in health, health care, and biomedical science and technology. The key messages from these meetings are outlined in the Special Publication Priorities on the Health Horizon: Informing PCORI's Strategic Plan. Given the breadth of the domains considered in the Priorities on the Health Horizon meetings—emerging technologies, social and environmental factors, optimizing value, and infrastructure—a formidable set of pressing health and health care research needs were reviewed and discussed. In addition, certain fundamental strategic priorities emerged as basic and critical to progress in the field: (1) the need to reorient research perspectives and activities to patient and family priorities and values, and in particular, those conditions that drive inequities; (2) the need to foster strategic learning partnerships across groups, organizations, and sectors; and (3) the need to build the continuous learning infrastructure to produce new insights at the pace and scale necessary for health and health care improvement. Moving forward, building the capacity to continuously improve learning and sharing throughout the system will entail stakeholders working together as seamlessly as possible. The NAM and PCORI worked together to facilitate an expansive dialogue with key stakeholders and engender trust through a focus on shared commitments to progress on improving health for all Americans in the decade ahead. Table of ContentsFront MatterExecutive Summary1 Introduction and Overview2 Technologies3 Social and Environmental Factors4 Optimizing Value5 Infrastructure6 Cross-Cutting Themes7 Patients Shaping the Health Horizon8 Strategic Priorities for the Field9 Concluding InsightsReferencesAppendix A: Topic Briefs for March 1516, 2021 MeetingAppendix B: Slide Presentations for March 1516, 2021 MeetingAppendix C: Agenda for March 1516, 2021 MeetingAppendix D: Agenda for April 27, 2021 MeetingAppendix E: Presenter and Facilitator Biographies for March 1516, 2021 MeetingAppendix F: Presenter and Facilitator Biographies for April 27, 2021 MeetingAppendix G: Participants for March 1516, 2021 MeetingAppendix H: Participants for April 27, 2021 Meeting

DKK 279.00
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The Public Health Effects of Food Deserts - National Research Council - Bog - National Academies Press - Plusbog.dk

Public Engagement and Clinical Trials - Development Forum On Drug Discovery - Bog - National Academies Press - Plusbog.dk

Improving Consent and Response in Longitudinal Studies of Aging - Improving Consent And Response In Longitudinal Studies Of Aging: A Workshop - Bog -

Supporting Family and Community Investments in Young Children Globally - Division Of Behavioral And Social Sciences And Education - Bog - National

Supporting Family and Community Investments in Young Children Globally - Division Of Behavioral And Social Sciences And Education - Bog - National

To examine the science, policy, and practice surrounding supporting family and community investments in young children globally and children in acute disruptions, the National Academies of Sciences, Engineering, and Medicine held a workshop in partnership with the Ethiopian Academy of Sciences in Addis Ababa, Ethiopia, from July 27-29, 2015. The workshop examined topics related to supporting family and community investments in young children globally. Examples of types of investments included financial and human capital. Participants also discussed how systems can better support children, families, and communities through acute disruptions such as the Ebola outbreak. Over the course of the 3-day workshop, researchers, policy makers, program practitioners, funders, young influencers, and other experts from 19 countries discussed how best to support family and community investments across areas of health, education, nutrition, social protection, and other service domains. This report summarizes the presentations and discussions from the workshop. Table of ContentsFront Matter1 Introduction and Overview2 Defining Family and Community Investments in Context3 Financing Models4 Policies Supporting Family and Community Investments5 Program Perspectives6 Community Voices7 Ebola and Acute Disruptions8 Aspirations for Young Children GloballyReferencesAppendix A: Abbreviations and AcronymsAppendix B: Workshop AgendaAppendix C: Biographical Sketches of Workshop Speakers

DKK 318.00
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International Animal Research Regulations - Institute For Laboratory Animal Research - Bog - National Academies Press - Plusbog.dk

International Animal Research Regulations - Institute For Laboratory Animal Research - Bog - National Academies Press - Plusbog.dk

Animals are widely used in neuroscience research to explore biological mechanisms of nervous system function, to identify the genetic basis of disease states, and to provide models of human disorders and diseases for the development of new treatments. To ensure the humane care and use of animals, numerous laws, policies, and regulations are in place governing the use of animals in research, and certain animal regulations have implications specific to neuroscience research. To consider animal research regulations from a global perspective, the IOM Forum on Neuroscience and Nervous System Disorders, in collaboration with the National Research Council and the Institute for Laboratory Animal Research, held a workshop in Buckinghamshire, UK, July 26-27, 2011. The workshop brought together neuroscientists, legal scholars, administrators, and other key stakeholders to discuss current and emerging trends in animal regulations as they apply to the neurosciences. This document summarizes the workshop. Table of ContentsFront Matter1 Introduction and Overview2 The Evolving Regulatory Environment3 Emerging Legal Trends Impacting Animal Research4 Animals in Neuroscience Research5 Advancing the 3Rs in Neuroscience Research6 Public Engagement and Animal Research Regulations7 Core Principles for the Care and Use of Animals in Research8 Summary of Workshop TopicsAppendix A: ReferencesAppendix B: Workshop AgendaAppendix C: Registered Attendees

DKK 240.00
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Enhancing Federal Clean Energy Innovation - Board On Energy And Environmental Systems - Bog - National Academies Press - Plusbog.dk

Enhancing Federal Clean Energy Innovation - Board On Energy And Environmental Systems - Bog - National Academies Press - Plusbog.dk

A widespread and rapid transition to a low-carbon energy system by 2050 is essential to keep pace with ambitious policy goals and avoid the worst consequences of climate change. Innovation is necessary to lower costs and improve performance of existing technologies and to develop new clean energy options that address challenges in harder-to-decarbonize sectors. To examine means by which the U.S. federal government can rise to this challenge, the National Academies of Sciences, Engineering, and Medicine hosted a virtual workshop series "Enhancing Federal Clean Energy Innovation" on July 27 to August 7, 2020. The workshop featured timely, action-orientated assessments of how to strengthen development and penetration of new clean energy technologies. This publication summarizes the presentations and discussions that occurred over the course of the workshop. Table of ContentsFront MatterOverview1 The Imperative to Accelerate Energy Innovation2 Strategies for Acceleration: Strengthening User Pull3 Strategies for Acceleration: Leveraging and Learning from the Department of Defense4 Managing the Department of Energy's Research and Development Portfolio5 Expert Roundtable6 Advanced Manufacturing and the Climate Crisis: Changes and Opportunities7 Thinking Globally8 Next StepsAppendixesAppendix A: Statement of TaskAppendix B: Workshop AgendaAppendix C: Planning Committee and Participant Biographical InformationAppendix D: Registered Workshop ParticipantsAppendix E: Acronyms

DKK 370.00
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Enhancing Urban Sustainability Infrastructure: Mathematical Approaches for Optimizing Investments - Division On Engineering And Physical Sciences -

Enhancing Urban Sustainability Infrastructure: Mathematical Approaches for Optimizing Investments - Division On Engineering And Physical Sciences -

The National Academies Board on Mathematical Sciences and Analytics and Board on Infrastructure and the Constructed Environment convened a 3-day public workshop on July 13, 20, and 27, 2022, to explore state-of-the-art analytical tools that could advance urban sustainability through improved prioritization of public works projects. Invited speakers included people working in urban sustainability, city planning, local public and private infrastructure, asset management, and infrastructure investment; city officials and utility officials; and statisticians, data scientists, mathematicians, economists, computer scientists, and artificial intelligence/machine learning experts. Presentations and workshop discussions provided insights into new research areas that have the potential to advance urban sustainability in public works planning, as well as the barriers to their adoption. This publication summarizes the presentation and discussion of the workshop. Table of ContentsFront MatterIntroduction1 Local Infrastructure Decision Making2 Relevant Data, Analytics, and Metrics for Infrastructure and Sustainability3 Funding and Investment Mechanisms for Infrastructure4 Decision Making for Infrastructure Investments5 Building Confidence in Data and Institutions6 Social, Physical, and Digital Infrastructure for Public Safety7 Moving Beyond Short-Termism8 Building the Ideal Sustainable City9 Workshop Themes and the Path ForwardAppendixesAppendix A: Key Resources for Decision MakersAppendix B: Workshop AgendaAppendix C: Biographical Information for Workshop Planning Committee Members and Speakers

DKK 208.00
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Improving the American Community Survey - Division Of Behavioral And Social Sciences And Education - Bog - National Academies Press - Plusbog.dk

Improving the American Community Survey - Division Of Behavioral And Social Sciences And Education - Bog - National Academies Press - Plusbog.dk

Since its origin 23 years ago as a pilot test conducted in four U.S. counties, the U.S. Census Bureau's American Community Survey (ACS) has been the focus of continuous research, development, and refinement. The survey cleared critical milestones 14 years ago when it began full-scale operations, including comprehensive nationwide coverage, and 5 years later when the ACS replaced a long-form sample questionnaire in the 2010 census as a source of detailed demographic and socioeconomic information. Throughout that existence and continuing today, ACS research and testing has worked to improve the survey's conduct in the face of challenges ranging from detailed and procedural to the broad and existential. This publication summarizes the presentations and discussion at the September 26-27, 2018, Workshop on Improving the American Community Survey (ACS), sponsored by the U.S. Census Bureau. Workshop participants explored uses of administrative records and third-party data to improve ACS operations and potential for boosting respondent participation through improved communication. Table of ContentsFront Matter1 Introduction2 Administrative Records, Third-Party Data, and the American Community Survey3 Increasing American Community Survey Participation Through Improved Respondent CommunicationReferencesAppendixesAppendix A: Workshop Agenda and Participant ListAppendix B: Biographical Sketches of Planning Committee Members and PresentersCommittee on National Statistics

DKK 370.00
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Characterization of Remote-Handled Transuranic Waste for the Waste Isolation Pilot Plant - National Research Council - Bog - National Academies Press

Characterization of Remote-Handled Transuranic Waste for the Waste Isolation Pilot Plant - National Research Council - Bog - National Academies Press

The U.S. Department of Energy (DOE) disposes of plutonium-contaminated debris from its 27 nuclear weapons facilities at the Waste Isolation Pilot Plant (WIPP), an underground repository in Carlsbad, New Mexico. After four years of operational experience, DOE has opportunities to make changes to the costly and time-consuming process of "characterizing" the waste to confirm that it is appropriate for shipment to and disposal at WIPP. The report says that in order to make such changes, DOE should conduct and publish a systematic and quantitative assessment to show that the proposed changes would not affect the protection of workers, the public, or the environment. Table of ContentsFront MatterExecutive Summary1 Introduction2 Remote-Handled Transuranic Waste3 Regulatory Context for the Disposal of Remote-Handled Transuranic Waste4 Department of Energy's Proposed Characterization Plan5 Assessment of the Proposed Characterization PlanReferencesAppendix A: Biographical Sketches of Committee MembersAppendix B: Information-Gathering MeetingsAppendix C: Excerpt from the Committee's Interim Report: Chapter 5Appendix D: DOE's Response to the Committee's Interim ReportAppendix E: Information About Selected Transuranic Waste Generator SitesAppendix F: Overview of the Contact-Handled Transuranic Waste Characterization PlanAppendix G: Non-Destructive Techniques for Remote-Handled Transuranic Waste CharacterizationAppendix H: Waste Dose Rates and Characterization Cost EstimatesAppendix I: GlossaryAppendix J: Acronyms

DKK 292.00
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Strengthening and Sustaining a Network of Public and Animal Health Clinical Laboratories in Pakistan - Pakistan Academy Of Sciences - Bog - National

Strengthening and Sustaining a Network of Public and Animal Health Clinical Laboratories in Pakistan - Pakistan Academy Of Sciences - Bog - National

As part of a multiyear project to promote a cooperative relationship between U.S. and Pakistani human and animal health and infectious disease experts, the Pakistan Academy of Sciences, together with the U.S. National Academies of Sciences, Engineering, and Medicine, convened a bilateral workshop in Islamabad, Pakistan, to promote best practices in and improved communications, cooperation, and coordination among public, private, military, and animal health clinical laboratories in Pakistan. The workshop, "Strengthening and Sustaining a Network of Public and Animal Health Clinical Laboratories in Pakistan," was held on September 27-29, 2016. Pakistani life science, public health, veterinary, and clinical laboratory experts, graduate students from Pakistani institutions of higher learning, and U.S. scientists/clinicians met at the workshop to explore questions facing human and animal health policy makers in Pakistan. This publication summarizes presentations and discussions of the workshop. Table of ContentsFront Matter1 Introduction2 Clinical Laboratory Networks for Human and Animal Health in Pakistan and North America3 Key Elements of Effective Clinical Labs and Laboratory Networks4 Effective Use of Clinical Laboratory Data5 Global Laboratory Networks: Integrating from the Ground Up6 Future Collaboration to Enhance Clinical Labs for Human and Animal Health7 ConclusionAppendix A: National Academies of Sciences, Engineering, and Medicine Planning Committee and Speaker BiosAppendix B: AgendaAppendix C: Additional Breakout Session Questions

DKK 182.00
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Developing Norms for the Provision of Biological Laboratories in Low-Resource Contexts - Policy And Global Affairs - Bog - National Academies Press -

Developing Norms for the Provision of Biological Laboratories in Low-Resource Contexts - Policy And Global Affairs - Bog - National Academies Press -

On June 27-28, 2018, the U.S. National Academies of Sciences, Engineering, and Medicine (the National Academies) convened an international workshop in Amsterdam, the Netherlands, on developing norms for the provision of laboratories in low-resource contexts. The U.S. Department of State's Biosecurity Engagement Program requested that the National Academies organize this workshop to engage an international group of organizations that provide funding for construction, upgrades, and maintenance of biological laboratories in countries without the means to build such labs themselves. Twenty-one people from 19 organizations participated. The intent was to advance the conversation about the identification and application of guiding principles and common norms for use by these organizations in their grants, partnerships, and aid. This publication summarizes the presentations and discussions from the workshop. Table of ContentsFront Matter1 INTRODUCTION2 THE NEED FOR CONTAINMENT LABORATORIES3 THE DONOR POPULATION AND ITS GOALS IN PROVIDING BIOLOGICAL LABORATORY CAPACITY FOR LOW-RESOURCE SETTINGS4 MOLECULAR DIAGNOSTICS: AN ALTERNATIVE TO HIGH CONTAINMENT?5 KEY FACTORS FOR BUILDING AND SUSTAINABLY OPERATING HIGH-CONTAINMENT LABS IN LOW-RESOURCE CONTEXTS: AN OVERVIEW6 POTENTIAL NORMS FOR FUNDERS OF BIOLOGICAL LABORATORIES IN LOW-RESOURCE COUNTRIESREFERENCESAPPENDIX A: STATEMENT OF TASKAPPENDIX B: WORKSHOP AGENDAAPPENDIX C: WORKSHOP PARTICIPANTS AND CONTRIBUTORSAPPENDIX D: WORLD BANK 2017 LIST OF LOW AND LOWER-MIDDLE INCOME ECONOMIESAPPENDIX E: LIST OF LABS IDENTIFIED IN LOW-RESOURCE COUNTRIES

DKK 370.00
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Informatics Needs and Challenges in Cancer Research - Board On Health Care Services - Bog - National Academies Press - Plusbog.dk

Informatics Needs and Challenges in Cancer Research - Board On Health Care Services - Bog - National Academies Press - Plusbog.dk

As information technology becomes an integral part of health care, it is important to collect and analyze data in a way that makes the information understandable and useful. Informatics tools—which help collect, organize, and analyze data—are essential to biomedical and health research and development. The field of cancer research is facing an overwhelming deluge of data, heightening the national urgency to find solutions to support and sustain the cancer informatics ecosystem. There is a particular need to integrate research and clinical data to facilitate personalized medicine approaches to cancer prevention and treatment—for example, tailoring treatment based on an individual patient's genetic makeup as well as that of the tumor—and to allow for more rapid learning from patient experiences. To further examine informatics needs and challenges for 21st century biomedical research, the IOM's National Cancer Policy Forum held a workshop February 27-28, 2012. The workshop was designed to raise awareness of the critical and urgent importance of the challenges, gaps and opportunities in informatics; to frame the issues surrounding the development of an integrated system of cancer informatics for acceleration of research; and to discuss solutions for transformation of the cancer informatics enterprise. Informatics Needs and Challenges in Cancer Research: Workshop Summary summarizes the workshop. Table of ContentsFront Matter1 Introduction2 Overview of the Cancer Informatics Landscape3 Informatics and Personalized Medicine4 Informatics-Supported Cancer Research Endeavors5 Potential Pathways and Models for Moving Forward6 Proposal for a Coalition of All Stakeholders7 Transforming Cancer Informatics: From Silos to SystemsAcronymsAppendix A: Workshop AgendaAppendix B: Speaker, Moderator, and Panelist Biographies

DKK 279.00
1

Climate Security in South Asia - Division Of Behavioral And Social Sciences And Education - Bog - National Academies Press - Plusbog.dk

Climate Security in South Asia - Division Of Behavioral And Social Sciences And Education - Bog - National Academies Press - Plusbog.dk

The South Asia region presents a confluence of major climate impacts and key security issues. From a weather and climate standpoint, the region experiences a wide range of hazards, such as the recent heatwaves, droughts, storms, and floods that have upended the lives and livelihoods of millions of people. From a demographic and socioeconomic standpoint, the region is experiencing rapid transformations and progress, even as fundamental challenges such as poverty and inequality persist. From a security standpoint, the region is the setting for a range of social and political dynamics that impact U.S. interests, including conflict at national and subnational levels; regional rivalries; and the imprint of global geopolitics. On October 26-27, 2022, the National Academies of Sciences, Engineering, and Medicine, under the auspices of the National Academies Climate Security Roundtable, convened a workshop to explore climate security in South Asia. Over two days, workshop participants considered some of the underlying climate, development, and geopolitical dynamics at play in the South Asia region; explored a set of historical case studies and future scenarios for climate change and security in South Asia; and they considered the available tools for analysis and forecasting climate-related risks. This publication summarizes the presentations and discussion of the workshop. Table of ContentsFront MatterWorkshop Overview1 Introduction2 Climate, Development, and Security Challenges in South Asia3 Historical Case Studies4 Possible Futures5 Tools for Analysis and Forecasting6 Reflecting on Climate Security Risk in South AsiaReferencesAppendix A: National Academies Climate Security RoundtableAppendix B: Workshop AgendaAppendix C: Workshop Planning Committee Biographical SketchesAppendix D: Workshop Speaker Biographical Sketches

DKK 182.00
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Views of the U.S. National Academies of Sciences, Engineering, and Medicine on Agenda Items at Issue at the World Radiocommunication Conference 2023 -

Views of the U.S. National Academies of Sciences, Engineering, and Medicine on Agenda Items at Issue at the World Radiocommunication Conference 2023 -

The radio frequency spectrum is a limited resource for which there is an ever-increasing demand from an expansive range of applications - all the way from commercial, such as mobile phones, to scientific, such as hurricane monitoring from space. Since radio waves do not stop at national borders, international regulation is necessary to ensure effective use of the radio spectrum for all parties. Use of the radio spectrum is regulated internationally by the Radio Regulations (RR), an international treaty. The International Telecommunication Union (ITU) has as its mission the facilitation of the efficient and interference-free use of the radio spectrum. Every 2 to 5 years, the ITU convenes a World Radiocommunication Conference (WRC) to review and revise the international RR. Changes to the RR are formulated through proposals to the conference according to Agenda Items, which are agreed on at the previous WRC. At the request of the National Science Foundation and the National Aeronautics and Space Administration, this report provides guidance to U.S. spectrum managers and policymakers as they prepare for the 2023 WRC to protect the scientific exploration of Earth and the universe using the radio spectrum. This report identifies the 2023 agenda items of relevance to U.S. radio astronomers and Earth remote sensing researchers, along with proposed agenda items for the 2027 WRC. Table of ContentsFront Matter1 Introduction2 Views of the U.S. National Academies of Sciences, Engineering, and Medicine on Selected WRC-23 and WRC-27 Agenda ItemsAppendixesAppendix A: Statement of TaskAppendix B: Acronyms and Abbreviations

DKK 292.00
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Rapid Medical Countermeasure Response to Infectious Diseases - Forum On Medical And Public Health Preparedness For Catastrophic Events - Bog -

Rapid Medical Countermeasure Response to Infectious Diseases - Forum On Medical And Public Health Preparedness For Catastrophic Events - Bog -

Emerging infectious disease threats that may not have available treatments or vaccines can directly affect the security of the world's health since these diseases also know no boundaries and will easily cross borders. Sustaining public and private investment in the development of medical countermeasures (MCMs) before an emerging infectious disease becomes a public health emergency in the United States has been extremely challenging. Interest and momentum peak during a crisis and wane between events, and there is little interest in disease threats outside the United States until they impact people stateside. On March 26 and 27, 2015, the Institute of Medicine convened a workshop in Washington, DC to discuss how to achieve rapid and nimble MCM capability for new and emerging threats. Public- and private-sector stakeholders examined recent efforts to prepare for and respond to outbreaks of Ebola Virus Disease, pandemic influenza, and coronaviruses from policy, budget, and operational standpoints. Participants discussed the need for rapid access to MCM to ensure national security and considered strategies and business models that could enhance stakeholder interest and investment in sustainable response capabilities. This report summarizes the presentations and discussions from this workshop. Table of ContentsFront Matter1 Introduction2 A Wake-Up Call: The 2014 Ebola Outbreak Response3 Preparedness as an Issue of National Security4 Rapid Development of Ebola Vaccines5 Influenza Risk Assessment and Pandemic Preparedness6 Developing MCMs for Coronaviruses7 Sustainable Business Models to Ensure Rapid and Nimble Responses8 Supporting MCM Development Across Threats and Funding CyclesA ReferencesB Acronyms and AbbreviationsC Statement of TaskD AgendaE Biosketches of Invited Speakers and Facilitators

DKK 318.00
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Frontiers of Engineering - National Academy Of Engineering - Bog - National Academies Press - Plusbog.dk

Frontiers of Engineering - National Academy Of Engineering - Bog - National Academies Press - Plusbog.dk

This volume of Frontiers of Engineering presents papers on the topics covered at the National Academy of Engineering's 2019 US Frontiers of Engineering Symposium, hosted by Boeing in North Charleston, South Carolina, September 25-27. At the annual 2 1/2-day event, 100 of this country's best and brightest early-career engineers - from academia, industry, and government and a variety of engineering disciplines - learn from their peers about pioneering work in different areas of engineering. Frontiers of Engineering conveys the excitement of this unique meeting and highlights innovative developments in engineering research and technical work. Table of ContentsFront Matter ADVANCED MANUFACTURING IN THE AGE OF DIGITAL TRANSFORMATIONAdvanced Manufacturing in the Age of Digital Transformation - Li Chang and Tarik DickensComputational Materials for the Design and Qualification of Additively Manufactured Components - Christapher G. LangRobots That Walk: What the Challenge of Locomotion Says About Next-Generation Manufacturing - Christian HubickiThe Digital Twin Concept - Pamela A. Kobryn ENGINEERING THE GENOMEEngineering the Genome - Charles Gersbach and Renee WegrzynGenome Editing with Precision and Accuracy - Krishanu SahaUsing CRISPR to Combat Human Disease Vectors - Omar S. AkbariMicrobes and Manufacturing: Moore's Law Meets Biology - Patrick BoyleEmpowering Genome Editing Through Standards - Samantha Maragh SELF-DRIVING CARS: TECHNOLOGY AND ETHICSSelf-Driving Cars: Technology and Ethics - Christoffer Heckman and Hae-Jong SeoPerceptions of Low-Cost Autonomous Driving - Tae Eun Choe, Xiaoshu Liu, Guang Chen, Weide Zhang, Yuliang Guo, and Ka Wai TsoiWhy Everyone Has It Wrong About the Ethics of Autonomous Vehicles - John Basl and Jeff BehrendsInfluencing Interactions Between Human Drivers and Autonomous Vehicles - Dorsa Sadigh BLOCKCHAIN TECHNOLOGYBlockchain Technology - Petr Novotny and Elaine ShiBlockchain Beyond Cryptocurrency: An Overview - Hong WanCryptocurrencies as Marketplaces - Jacob Leshno APPENDIXESContributorsParticipantsProgram

DKK 318.00
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Frontiers of Engineering - National Academy Of Engineering - Bog - National Academies Press - Plusbog.dk

Frontiers of Engineering - National Academy Of Engineering - Bog - National Academies Press - Plusbog.dk

This volume presents papers on the topics covered at the National Academy of Engineering's 2017 US Frontiers of Engineering Symposium. Every year the symposium brings together 100 outstanding young leaders in engineering to share their cutting-edge research and innovations in selected areas. The 2017 symposium was held September 25-27 at the United Technologies Research Center in East Hartford, Connecticut. The intent of this book is to convey the excitement of this unique meeting and to highlight innovative developments in engineering research and technical work. Table of ContentsFront MatterMACHINES THAT TEACH THEMSELVESMachines That Teach Themselves - Rajan BhattacharyyaHumans and Computers Working Together to Measure Machine Learning Interpretability - Jordan Boyd-GraberENERGY STRATEGIES TO POWER OUR FUTUREEnergy Strategies to Power Our Future - Katherine Dykes and Jeremy MundayAgile Fractal Systems: Reenvisioning Power System Architecture - Timothy D. Heidel and Craig MillerBig Data and Analytics for Wind Energy Operations and Maintenance: Opportunities, Trends, and Challenges in the Industrial Internet - Bouchra BouqataAcross Dimensions and Scales: How Imaging and Machine Learning Will Help Design Tomorrow's Energy Conversion Devices - Mariana BertoniWireless Charging of Electric Vehicles - Khurram AfridiUNRAVELING THE COMPLEXITY OF THE BRAINUnraveling the Complexity of the Brain - Xue Han and Maryam M. ShanechiTechnologies to Interface with the Brain for Recording and Modulation - Ellis MengBrain-Machine Interface Paradigms for Neuroscience and Clinical Translation - Samantha R. Santacruz, Vivek R. Athalye, Ryan M. Neely, and Jose M. CarmenaThe Roles of Machine Learning in Biomedical Science - Konrad Paul Kording, Ari S. Benjamin, Roozbeh Farhoodi, and Joshua I. GlaserEfficient Feature Extraction and Classification Methods in Neural Interfaces - Mahsa Shoaran, Benyamin A. Haghi, Masoud Farivar, and Azita EmamiMEGATALL BUILDINGS AND OTHER FUTURE PLACES OF WORKMegatall Buildings and Other Future Places of Work - Maria Paz Gutierrez and Marija TrckaThe Evolution of Elevators: Physical-Human Interface, Digital Interaction, and Megatall Buildings - Stephen R. NicholsSupertall Timber: Functional Natural Materials for High-Rise Structures - Michael H. RamageApplications of Insights from Biology and Mathematics to the Design of Material Structures - Jenny E. SabinAPPENDIXESContributorsParticipantsProgram

DKK 292.00
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Refining Processes for the Co-Development of Genome-Based Therapeutics and Companion Diagnostic Tests - Institute Of Medicine - Bog - National

Refining Processes for the Co-Development of Genome-Based Therapeutics and Companion Diagnostic Tests - Institute Of Medicine - Bog - National

Many drug developers have examined new strategies for creating efficiencies in their development processes, including the adoption of genomics-based approaches. Genomic data can identify new drug targets for both common and rare diseases, can predict which patients are likely to respond to a specific treatment, and has the potential to significantly reduce the cost of clinical trials by reducing the number of patients that must be enrolled in order to demonstrate safety and efficacy. A key component of the approval of targeted therapeutics is the ability to identify the population of patients who will benefit from treatment, and this has largely hinged on the co-development and co-submission to the FDA of a companion diagnostic test.The co-development process, or the development of the test and drug for the simultaneous submission to FDA, has led to a major alteration in the way that drugs are being developed, with traditionally separate entities—pharmaceutical and diagnostic companies—now working in close collaboration. Refining Processes for the Co-Development of Genome-Based Therapeutics and Companion Diagnostic Tests is the summary of a workshop held by the Roundtable on Translating Genomic-Based Research for Health on February 27, 2013 to examine and discuss challenges and potential solutions for the codevelopment of targeted therapeutics and companion molecular tests for the prediction of drug response. Prior to the workshop, key stakeholders, including laboratory and medical professional societies, were individually asked to provide possible solutions to resolve the concerns raised about co-development of companion diagnostic tests and therapies. Workshop speakers were charged with addressing these solutions in their presentations by providing insight on (1) whether the proposed solutions address the problems described, (2) whether there are other solutions to propose, and (3) what steps could be taken to effectively implement the proposed solutions.Table of ContentsFront Matter1 Introduction2 Regulatory Perspectives3 Perspectives from Patients, Providers, and Laboratory Representatives4 Perspectives of Diagnostic Test and Pharmaceutical Developers5 Perspectives of Payers and Regulators6 Concluding ObservationsReferencesAppendix A: Workshop AgendaAppendix B: Speaker Biographical SketchesAppendix C: Statement of TaskAppendix D: Registered Attendees

DKK 240.00
1