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Algorithms for Sample Preparation with Microfluidic Lab-on-Chip - Sukanta Bhattacharjee - Bog - River Publishers - Plusbog.dk

Algorithms for Sample Preparation with Microfluidic Lab-on-Chip - Sukanta Bhattacharjee - Bog - River Publishers - Plusbog.dk

Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound impact on various application domains such as clinical diagnostics, DNA analysis, genetic engineering, and drug discovery, among others. They are capable of precisely manipulating micro-/pico-liter quantities of fluids, and provide integrated support for mixing, storage, transportation, and sensing, on-chip. In almost all bioprotocols, sample preparation plays an important role, which includes dilution and mixing of several fluids satisfying certain volumetric ratios. However, designing algorithms that minimize reactant-cost and sample-preparation time suited for microfluidic chips poses a great challenge from the perspective of protocol mapping, scheduling, and physical design. Algorithms for Sample Preparation with Microfluidic Lab-on-Chip attempts to bridge the widening gap between biologists and engineers by introducing, from the fundamentals, several state-of-the-art computer-aided-design (CAD) algorithms for sample preparation with digital and flow-based microfluidic biochips. Technical topics discussed in the book include: Basics of digital and flow-based microfluidic lab-on-chipComprehensive review of state-of-the-art sample preparation algorithmsSample-preparation algorithms for digital microfluidic lab-on-chipSample-preparation algorithms for flow-based microfluidic lab-on-chip

DKK 449.00
1

Algorithms for Sample Preparation with Microfluidic Lab-on-Chip - Sukanta Bhattacharjee - Bog - River Publishers - Plusbog.dk

Algorithms for Sample Preparation with Microfluidic Lab-on-Chip - Sukanta Bhattacharjee - Bog - River Publishers - Plusbog.dk

Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound impact on various application domains such as clinical diagnostics, DNA analysis, genetic engineering, and drug discovery, among others. They are capable of precisely manipulating micro-/pico-liter quantities of fluids, and provide integrated support for mixing, storage, transportation, and sensing, on-chip. In almost all bioprotocols, sample preparation plays an important role, which includes dilution and mixing of several fluids satisfying certain volumetric ratios. However, designing algorithms that minimize reactant-cost and sample-preparation time suited for microfluidic chips poses a great challenge from the perspective of protocol mapping, scheduling, and physical design. Algorithms for Sample Preparation with Microfluidic Lab-on-Chip attempts to bridge the widening gap between biologists and engineers by introducing, from the fundamentals, several state-of-the-art computer-aided-design (CAD) algorithms for sample preparation with digital and flow-based microfluidic biochips. Technical topics discussed in the book include: Basics of digital and flow-based microfluidic lab-on-chipComprehensive review of state-of-the-art sample preparation algorithmsSample-preparation algorithms for digital microfluidic lab-on-chipSample-preparation algorithms for flow-based microfluidic lab-on-chip

DKK 967.00
1

HVAC Fundamentals, Third Edition - Samuel C. Sugarman - Bog - River Publishers - Plusbog.dk

Coil tubing unit for oil production and remedial measures - Mohammed Ismail Iqbal - Bog - River Publishers - Plusbog.dk

Coil tubing unit for oil production and remedial measures - Mohammed Ismail Iqbal - Bog - River Publishers - Plusbog.dk

Well activation is one of the most important aspects in the oil and gas industries and nitrogen gas is predominately used. The gas, being light, is sent down the producing reservoir which will enhance the production or improve the flow of crude oil. In addition to the methods used to increase production there are several problems like sand production and water production from the producing wells. Sand production occurs when the destabilizing stresses at the formation face exceed the strength of the natural arching tendencies and/or grain-to-grain cementation strength. Ideally, during oil production, the formation should be porous, permeable and well consolidated through which hydrocarbons can easily flow into the production wells. But sometimes, especially during production from unconsolidated sandstone reservoirs, the produced hydrocarbons may also carry large amounts of sand into the well bore and sand entering production wells is one of the oldest problems faced by oil companies and one of the toughest to solve. These unconsolidated formations may not restrain grain movement, and produce sand along with the fluids especially at high rates. Water production is also a problem that many reservoir or production engineers face in day-to-day life. As engineers we should be able to decide whether water control solutions should be applied or not. The excess production of water is caused by the depletion of the reservoir and simply sweeps away most of the oil that the reservoir can produce. This book gives an information how well activation using nitrogen is carried out, and how sand control and water control issues can be resolved.

DKK 449.00
1

Coil Tubing Unit for Oil Production and Remedial Measures - Mohammed Ismail Iqbal - Bog - River Publishers - Plusbog.dk

Coil Tubing Unit for Oil Production and Remedial Measures - Mohammed Ismail Iqbal - Bog - River Publishers - Plusbog.dk

Well activation is one of the most important aspects in the oil and gas industries and nitrogen gas is predominately used. The gas, being light, is sent down the producing reservoir which will enhance the production or improve the flow of crude oil. In addition to the methods used to increase production there are several problems like sand production and water production from the producing wells. Sand production occurs when the destabilizing stresses at the formation face exceed the strength of the natural arching tendencies and/or grain-to-grain cementation strength. Ideally, during oil production, the formation should be porous, permeable and well consolidated through which hydrocarbons can easily flow into the production wells. But sometimes, especially during production from unconsolidated sandstone reservoirs, the produced hydrocarbons may also carry large amounts of sand into the well bore and sand entering production wells is one of the oldest problems faced by oil companies and one of the toughest to solve. These unconsolidated formations may not restrain grain movement, and produce sand along with the fluids especially at high rates. Water production is also a problem that many reservoir or production engineers face in day-to-day life. As engineers we should be able to decide whether water control solutions should be applied or not. The excess production of water is caused by the depletion of the reservoir and simply sweeps away most of the oil that the reservoir can produce. This book gives an information how well activation using nitrogen is carried out, and how sand control and water control issues can be resolved.

DKK 967.00
1

Electronic System-Level HW/SW Co-Design of Heterogeneous Multi-Processor Embedded Systems - Luigi Pomante - Bog - River Publishers - Plusbog.dk

Electronic System-Level HW/SW Co-Design of Heterogeneous Multi-Processor Embedded Systems - Luigi Pomante - Bog - River Publishers - Plusbog.dk

Modern electronic systems consist of a fairly heterogeneous set of components. Today, a single system can be constituted by a hardware platform, frequently composed of a mix of analog and digital components, and by several software application layers. The hardware can include several heterogeneous microprocessors (e.g. GPP, DSP, GPU, etc.), dedicated ICs (ASICs and/or FPGAs), memories, a set of local connections between the system components, and some interfaces between the system and the environment (sensors, actuators, etc.). Therefore, on the one hand, multi-processor embedded systems are capable of meeting the demand of processing power and flexibility of complex applications. On the other hand, such systems are very complex to design and optimize, so that the design methodology plays a major role in determining the success of the products. For these reasons, to cope with the increasing system complexity, the approaches typically used today are oriented towards co-design methodologies working at the higher levels of abstraction. Unfortunately, such methodologies are typically customized for the specific application, suffer of a lack of generality and still need a considerable effort when real-size project are envisioned. Therefore, there is still the need for a general methodology able to support the designer during the high-level steps of a co-design flow, enabling an effective design space exploration before tackling the low-level steps and thus committing to the final technology. This should prevent costly redesign loops.In such a context, the work described in this book, composed of two parts, aims at providing models, methodologies and tools to support each step of the co-design flow of embedded systems implemented by exploiting heterogeneous multi-processor architectures mapped on distributed systems, as well as fully integrated onto a single chip.

DKK 357.00
1

Electronic System-Level HW/SW Co-Design of Heterogeneous Multi-Processor Embedded Systems - Luigi Pomante - Bog - River Publishers - Plusbog.dk

Electronic System-Level HW/SW Co-Design of Heterogeneous Multi-Processor Embedded Systems - Luigi Pomante - Bog - River Publishers - Plusbog.dk

Modern electronic systems consist of a fairly heterogeneous set of components. Today, a single system can be constituted by a hardware platform, frequently composed of a mix of analog and digital components, and by several software application layers. The hardware can include several heterogeneous microprocessors (e.g. GPP, DSP, GPU, etc.), dedicated ICs (ASICs and/or FPGAs), memories, a set of local connections between the system components, and some interfaces between the system and the environment (sensors, actuators, etc.). Therefore, on the one hand, multi-processor embedded systems are capable of meeting the demand of processing power and flexibility of complex applications. On the other hand, such systems are very complex to design and optimize, so that the design methodology plays a major role in determining the success of the products. For these reasons, to cope with the increasing system complexity, the approaches typically used today are oriented towards co-design methodologies working at the higher levels of abstraction. Unfortunately, such methodologies are typically customized for the specific application, suffer of a lack of generality and still need a considerable effort when real-size project are envisioned. Therefore, there is still the need for a general methodology able to support the designer during the high-level steps of a co-design flow, enabling an effective design space exploration before tackling the low-level steps and thus committing to the final technology. This should prevent costly redesign loops.In such a context, the work described in this book, composed of two parts, aims at providing models, methodologies and tools to support each step of the co-design flow of embedded systems implemented by exploiting heterogeneous multi-processor architectures mapped on distributed systems, as well as fully integrated onto a single chip.

DKK 778.00
1

Smart Grid Planning and Implementation - P.e. Gellings - Bog - River Publishers - Plusbog.dk

Testing and Balancing HVAC Air and Water Systems - Samuel C. Sugarman - Bog - River Publishers - Plusbog.dk

Testing and Balancing HVAC Air and Water Systems - Samuel C. Sugarman - Bog - River Publishers - Plusbog.dk

This thoroughly revised book will provide the reader with an understanding of the principles and practices of testing and balancing (TAB) heating, ventilating and air conditioning (HVAC) air and water systems. It is for anyone interested in testing and balancing. For the novice and the experienced testing and balancing technician, it is a field reference book of procedures, equations, and information tables. For those interested in getting into TAB or who are new to the HVAC industry, it is a text for learning more about HVAC systems and testing and balancing. For the mechanical engineer, building owner, facility manager, commissioning agency or energy manager, this book can be used for teaching TAB, writing more effective specifications, and learning about TAB and how it interacts with system commissioning, indoor air quality and energy management. It is the intent of this book to improve the communications between owners, mechanical engineers, designers, vendors, contractors, TAB engineers, supervisors, and technicians to ensure that HVAC systems are being thoroughly tested and balanced. This book is used in test and balance self-study courses, in-house training programs, seminars, and other training formats as preparation for TAB certification, and as a text in colleges and technical schools. The sixth edition has general and specific testing and balancing procedures for constant air volume systems, variable air volume systems, return air and exhaust air systems, positive and negative pressure conditioned spaces, and fans and fan performance in Chapters 1 through 9. Chapters 10–12 cover testing and balancing fume hood systems, and cleanrooms and commissioning HVAC systems. Chapters 13 and 14 provide information on water systems and centrifugal pumps including water balancing procedures using flow meters, system components and temperatures, and water pumps and pump performance. Chapter 15 reviews analog and digital controls. Chapters 16–20 cover terminology for fluid flow, psychrometrics, refrigeration¸ air distribution, water distribution, fans and pumps, motors, electrical, and instrument usage and care. Chapters 21 and 22 are equations and tables.

DKK 542.00
1

Sensors and Measurement Systems - Walter Lang - Bog - River Publishers - Plusbog.dk

Sensors and Measurement Systems - Walter Lang - Bog - River Publishers - Plusbog.dk

Sensors and Measurement Systems - Walter (university Of Bremen Lang - Bog - River Publishers - Plusbog.dk

Advances in Applied Mathematical Analysis and Applications - - Bog - River Publishers - Plusbog.dk

Advances in Applied Mathematical Analysis and Applications - - Bog - River Publishers - Plusbog.dk

Artificial Intelligence and Blockchain in Digital Forensics - - Bog - River Publishers - Plusbog.dk

Artificial Intelligence and Blockchain in Digital Forensics - - Bog - River Publishers - Plusbog.dk

Digital forensics is the science of detecting evidence from digital media like a computer, smartphone, server, or network. It provides the forensic team with the most beneficial methods to solve confused digital-related cases. AI and blockchain can be applied to solve online predatory chat cases and photo forensics cases, provide network service evidence, custody of digital files in forensic medicine, and identify roots of data scavenging. The increased use of PCs and extensive use of internet access, have meant easy availability of hacking tools. Over the past two decades, improvements in the information technology landscape have made the collection, preservation, and analysis of digital evidence extremely important. The traditional tools for solving cybercrimes and preparing court cases are making investigations difficult. We can use AI and blockchain design frameworks to make the digital forensic process efficient and straightforward. AI features help determine the contents of a picture, detect spam email messages and recognize swatches of hard drives that could contain suspicious files. Blockchain-based lawful evidence management schemes can supervise the entire evidence flow of all of the court data. This book provides a wide-ranging overview of how AI and blockchain can be used to solve problems in digital forensics using advanced tools and applications available on the market.

DKK 1042.00
1

Basic VLSI Design Technology - Cherry Bhargava - Bog - River Publishers - Plusbog.dk

Basic VLSI Design Technology - Cherry Bhargava - Bog - River Publishers - Plusbog.dk

The current cutting-edge VLSI circuit design technologies provide end-users with many applications, increased processing power and improved cost effectiveness. This trend is accelerating, with significant implications on future VLSI and systems design. VLSI design engineers are always in demand for front-end and back-end design applications.The book aims to give future and current VSLI design engineers a robust understanding of the underlying principles of the subject. It not only focuses on circuit design processes obeying VLSI rules but also on technological aspects of fabrication. The Hardware Description Language (HDL) Verilog is explained along with its modelling style. The book also covers CMOS design from the digital systems level to the circuit level. The book clearly explains fundamental principles and is a guide to good design practices.The book is intended as a reference book for senior undergraduate, first-year post graduate students, researchers as well as academicians in VLSI design, electronics & electrical engineering and materials science. The basics and applications of VLSI design from digital system design to IC fabrication and FPGA Prototyping are each covered in a comprehensive manner. At the end of each unit is a section with technical questions including solutions which will serve as an excellent teaching aid to all readers.Technical topics discussed in the book include: • Digital System Design• Design flow for IC fabrication and FPGA based prototyping • Verilog HDL• IC Fabrication Technology• CMOS VLSI Design• Miscellaneous (It covers basics of Electronics, and Reconfigurable computing, PLDs, Latest technology etc.).

DKK 967.00
1

Elementary Vector Calculus and Its Applications with MATLAB Programming - Jitendra Panchal - Bog - River Publishers - Plusbog.dk

Elementary Vector Calculus and Its Applications with MATLAB Programming - Jitendra Panchal - Bog - River Publishers - Plusbog.dk

Sir Isaac Newton, one of the greatest scientists and mathematicians of all time, introduced the notion of a vector to define the existence of gravitational forces, the motion of the planets around the sun, and the motion of the moon around the earth. Vector calculus is a fundamental scientific tool that allows us to investigate the origins and evolution of space and time, as well as the origins of gravity, electromagnetism, and nuclear forces. Vector calculus is an essential language of mathematical physics, and plays a vital role in differential geometry and studies related to partial differential equations widely used in physics, engineering, fluid flow, electromagnetic fields, and other disciplines. Vector calculus represents physical quantities in two or three-dimensional space, as well as the variations in these quantities. The machinery of differential geometry, of which vector calculus is a subset, is used to understand most of the analytic results in a more general form. Many topics in the physical sciences can be mathematically studied using vector calculus techniques. This book is designed under the assumption that the readers have no prior knowledge of vector calculus. It begins with an introduction to vectors and scalars, and also covers scalar and vector products, vector differentiation and integrals, Gauss''s theorem, Stokes''s theorem, and Green''s theorem. The MATLAB programming is given in the last chapter. This book includes many illustrations, solved examples, practice examples, and multiple-choice questions.

DKK 1042.00
1

Basic VLSI Design Technology - Cherry Bhargava - Bog - River Publishers - Plusbog.dk

Basic VLSI Design Technology - Cherry Bhargava - Bog - River Publishers - Plusbog.dk

The current cutting-edge VLSI circuit design technologies provide end-users with many applications, increased processing power and improved cost effectiveness. This trend is accelerating, with significant implications on future VLSI and systems design. VLSI design engineers are always in demand for front-end and back-end design applications.The book aims to give future and current VSLI design engineers a robust understanding of the underlying principles of the subject. It not only focuses on circuit design processes obeying VLSI rules but also on technological aspects of fabrication. The Hardware Description Language (HDL) Verilog is explained along with its modelling style. The book also covers CMOS design from the digital systems level to the circuit level. The book clearly explains fundamental principles and is a guide to good design practices.The book is intended as a reference book for senior undergraduate, first-year post graduate students, researchers as well as academicians in VLSI design, electronics & electrical engineering and materials science. The basics and applications of VLSI design from digital system design to IC fabrication and FPGA Prototyping are each covered in a comprehensive manner. At the end of each unit is a section with technical questions including solutions which will serve as an excellent teaching aid to all readers.Technical topics discussed in the book include: • Digital System Design• Design flow for IC fabrication and FPGA based prototyping • Verilog HDL• IC Fabrication Technology• CMOS VLSI Design• Miscellaneous (It covers basics of Electronics, and Reconfigurable computing, PLDs, Latest technology etc.).

DKK 457.00
1

SMART Integrated Circuit Design and Methodology - - Bog - River Publishers - Plusbog.dk

SMART Integrated Circuit Design and Methodology - - Bog - River Publishers - Plusbog.dk

This book describes advanced flows and methodologies for the design and implementation of system-on-chip (SoC). It is written by a mixture of industrial experts and key academic professors and researchers. The intended audience is not only students but also engineers with system-on-chip and semiconductor background currently working in the semiconductor industry. Integrated Circuits are available in every electronic product, especially in emerging market segments such as 5G mobile communications, autonomous driving, fully electrified vehicles, and artificial intelligence. These product types require real-time processing at billions of operations per second. The development design cycle time is driving costs and time to market more than ever before. The traditional design methodologies have reached their limits and innovative solutions are essential to serve the emerging SoC design challenges. In the framework of the Circuit and System Society (CASS) Outreach Initiative 2022 call, the SMART Integrated Circuits design methodology – named SMARTIC – Seasonal School was performed in November 2022, in Thessaloniki (Greece). Features - Core analog circuits of any system of chip, such as high-performance rectifiers and filters, are addressed in detail, together with their respective design methodology. - New advanced methodologies towards design cycle speed up based on machine learning and artificial intelligence applications. - Advanced analog design methodology based on gm/Id and lock up tables. A powerful flow for enabling fast time to market analog circuit design focusing on baseband circuits - More exotic methodologies and applications with focus on digital-based analog processing in nanoscale CMOS ICs and the design and development of depleted monolithic active pixel sensors for high-radiation applications, together with all the respective challenges of this application.

DKK 967.00
1

Thyroid Systems Engineering - Simon Goede - Bog - River Publishers - Plusbog.dk

Thyroid Systems Engineering - Simon Goede - Bog - River Publishers - Plusbog.dk

In recent years, a considerable amount of effort has been devoted, both in industry and academia, towards the behavioral modeling, evaluation and prediction of the hypothalamus pituitary thyroid system.Thyroid Systems Engineering targets an optimal treatment of people suffering from thyroid hormone disorders. The content is motivated by in-depth observations of such patients whose rich data supported the theoretical framework arising from formal mathematical reasoning, guided by the nature of thyroid physiology. Leveraging on the insights emerging from the unique combination of an electrical engineer working with a clinical thyroidologist, and both being scientists skilled in mathematics, the authors introduce this new discipline and field of scientific investigation aptly designated as Thyroid Systems Engineering.Readers will discover that mathematics can indeed model the behavior of the hypothalamus-pituitary-thyroid (HPT) axis. Focused on modeling, each of the eighteen chapters gives the reader a notion of the application of relevant mathematics to pertinent issues encountered in mainstream thyroidology. Many cellular processes resemble the flux of variables and states in a complex multi-parameter space through time analogous to current flow in electrical networks. It is then logical to apply the principles and physical laws of electrodynamics, electrical network theory, control systems theory and signal theory to many of the biological phenomena encountered in endocrinology. Such an approach is used liberally throughout the book and successfully yields elegant solutions to a number of models presented within.This book can serve as a reference to mathematical modeling in other aspects of endocrine physiology, and as the starting point for a fundamental course in medical modeling. It will appeal to postgraduates in electrical engineering, academic physicians and biomedical researchers. Further, readers equipped with advanced calculus, electrical network theory, control theory and signal theory should be able to follow the mathematical expositions that describe thyrotropic control. They represent a new discipline based on mathematical modeling in physiology applicable to medical diagnostics, measurement and treatment to cooperate in the clinical team and realize an optimized treatment for patients.

DKK 920.00
1

Atlas of Cilia Bioengineering and Biocomputing - - Bog - River Publishers - Plusbog.dk

Atlas of Cilia Bioengineering and Biocomputing - - Bog - River Publishers - Plusbog.dk

Cilia are microscopic finger-like cell-surface organelles possessed by a great many eukaryotic organisms, including humans, whose purposes include generating local fluid movements via rhythmic whip-like beating and environmental sensing. Despite intense research efforts since their discovery by van Leeuwenhoek in the 1670''s, several key questions regarding ciliary functions, experimental manipulation and in silico imitation remain unanswered. Major justifications for cilia research lie in their involvement in various forms of human disease (ciliopathies) and their ability to instantiate decentralised, asynchronous sensorial-actuation of adjacent matter through modulation of beating characteristics. Further elucidation of these characteristics, which is a problem requiring the combined expertise of mathematicians, computer scientists, engineers and life scientists, will lead to novel biomedical therapies, creation of `smart'' actuating surfaces for microfluidics/lab-on-chip applications and a greater understanding of fluid mechanics in real-world scenarios. This lavishly-illustrated anthology presents recent advances in the fields of ciliary investigation, manipulation, emulation, mimesis and modelling from key researchers in their fields: its goal is to explain the state-of-the-art in cilia bioengineering and bio-computation in a uniquely creative, accessible manner, towards encouraging further transdisciplinary work in the field as well as educating a broad spectrum of scientists and lay people. The volume is split into three distinct but interwoven themes:Biology: Biological preliminaries for the study of cilia; the state-of-the-art in genetic engineering of ciliated cells for biomedical purposes; reprogramming of cilia dynamics in live cells.Engineering: Creation of macro cilia robots for object sorting applications; pneumatic cilia for the optimization of fluid motion; electrostatic, magnetic and MEMS cilia for microfluidic mixing; reviews in artificial cilia fabrication, actuation and flow induction methods.Numerical and computational modelling. Analyses of thin film cilia for `lab on chip'' microfluidic mixing applications; modelling of gel-based artificial cilia towards simulating dynamic behaviors of responsive cilia layers in complex fluids across a wide range of potential applications.

DKK 422.00
1

Engineering of Music for the Digital Age - Jeffrey Ewing - Bog - River Publishers - Plusbog.dk

Engineering of Music for the Digital Age - Jeffrey Ewing - Bog - River Publishers - Plusbog.dk

Musical scores – like literature, poetry, and technical manuals – are documents. The central tenet of this book is that musical composition in the digital age is a form of document engineering. In essence, music shares with other forms of creative content generation – from poetry to prose, and from science to science fiction – the need for structure, flow, and sources for creativity. Musical composition is considered in this book as the creative process of engineering musical documents with regards to its arrangement, form, texture, and instrumentation, etc. This "document" then instructs a performance or the creation of an alternative document, such as a recording. In this book, the arrangement of phrases, patterns, and structures seen in music will be illustrated to give new composers a starting point to begin planning and making decisions about their own compositions. The book will also guide those who need assistance in completing a piece. While this is a book about musical composition, it is not meant to be a manual on music theory. Instead, the book keeps its focus on the structural elements of a composition. Its aim is to give the audience a structural road map for composing; whether they are starting a piece from the first note, having a melody in mind already, or need help overcoming a creative hurdle. The book examines compositions that clearly define a form or technique. Among the key compositional elements are: - Form, Phrase, Period, and Expression in Composition - Rhythm/Motive - Melody and Harmony - Tonal Center - Mode Mixture and Modulation - Accompaniment/Instrumentation/Orchestration - Composition Techniques and Notation Targeted examples cover all stages of writing a piece, helping to build the reader’s composition from the first note into a complete work without promoting a style or harmonic practice. Each chapter contains a sidebar addressing helping the composer to add creative sources for the music making process. Finally, the book concludes with a chapter on creativity in terms of how composed music can affect our lives and even our fairy tales.

DKK 911.00
1

Thyroid Systems Engineering - Simon Goede - Bog - River Publishers - Plusbog.dk

Thyroid Systems Engineering - Simon Goede - Bog - River Publishers - Plusbog.dk

In recent years, a considerable amount of effort has been devoted, both in industry and academia, towards the behavioral modeling, evaluation and prediction of the hypothalamus pituitary thyroid system.Thyroid Systems Engineering targets an optimal treatment of people suffering from thyroid hormone disorders. The content is motivated by in-depth observations of such patients whose rich data supported the theoretical framework arising from formal mathematical reasoning, guided by the nature of thyroid physiology. Leveraging on the insights emerging from the unique combination of an electrical engineer working with a clinical thyroidologist, and both being scientists skilled in mathematics, the authors introduce this new discipline and field of scientific investigation aptly designated as Thyroid Systems Engineering.Readers will discover that mathematics can indeed model the behavior of the hypothalamus-pituitary-thyroid (HPT) axis. Focused on modeling, each of the eighteen chapters gives the reader a notion of the application of relevant mathematics to pertinent issues encountered in mainstream thyroidology. Many cellular processes resemble the flux of variables and states in a complex multi-parameter space through time analogous to current flow in electrical networks. It is then logical to apply the principles and physical laws of electrodynamics, electrical network theory, control systems theory and signal theory to many of the biological phenomena encountered in endocrinology. Such an approach is used liberally throughout the book and successfully yields elegant solutions to a number of models presented within.This book can serve as a reference to mathematical modeling in other aspects of endocrine physiology, and as the starting point for a fundamental course in medical modeling. It will appeal to postgraduates in electrical engineering, academic physicians and biomedical researchers. Further, readers equipped with advanced calculus, electrical network theory, control theory and signal theory should be able to follow the mathematical expositions that describe thyrotropic control. They represent a new discipline based on mathematical modeling in physiology applicable to medical diagnostics, measurement and treatment to cooperate in the clinical team and realize an optimized treatment for patients.

DKK 422.00
1

Atlas of Cilia Bioengineering and Biocomputing - - Bog - River Publishers - Plusbog.dk

Atlas of Cilia Bioengineering and Biocomputing - - Bog - River Publishers - Plusbog.dk

Cilia are microscopic finger-like cell-surface organelles possessed by a great many eukaryotic organisms, including humans, whose purposes include generating local fluid movements via rhythmic whip-like beating and environmental sensing. Despite intense research efforts since their discovery by van Leeuwenhoek in the 1670''s, several key questions regarding ciliary functions, experimental manipulation and in silico imitation remain unanswered. Major justifications for cilia research lie in their involvement in various forms of human disease (ciliopathies) and their ability to instantiate decentralised, asynchronous sensorial-actuation of adjacent matter through modulation of beating characteristics. Further elucidation of these characteristics, which is a problem requiring the combined expertise of mathematicians, computer scientists, engineers and life scientists, will lead to novel biomedical therapies, creation of `smart'' actuating surfaces for microfluidics/lab-on-chip applications and a greater understanding of fluid mechanics in real-world scenarios. This lavishly-illustrated anthology presents recent advances in the fields of ciliary investigation, manipulation, emulation, mimesis and modelling from key researchers in their fields: its goal is to explain the state-of-the-art in cilia bioengineering and bio-computation in a uniquely creative, accessible manner, towards encouraging further transdisciplinary work in the field as well as educating a broad spectrum of scientists and lay people. The volume is split into three distinct but interwoven themes:Biology: Biological preliminaries for the study of cilia; the state-of-the-art in genetic engineering of ciliated cells for biomedical purposes; reprogramming of cilia dynamics in live cells.Engineering: Creation of macro cilia robots for object sorting applications; pneumatic cilia for the optimization of fluid motion; electrostatic, magnetic and MEMS cilia for microfluidic mixing; reviews in artificial cilia fabrication, actuation and flow induction methods.Numerical and computational modelling. Analyses of thin film cilia for `lab on chip'' microfluidic mixing applications; modelling of gel-based artificial cilia towards simulating dynamic behaviors of responsive cilia layers in complex fluids across a wide range of potential applications.

DKK 920.00
1

Circuit Design - Candido Duarte - Bog - River Publishers - Plusbog.dk

Circuit Design - Candido Duarte - Bog - River Publishers - Plusbog.dk

Circuit Design = Science + Art! Designers need a skilled "gut feeling" about circuits and related analytical techniques, plus creativity, to solve all problems and to adhere to the specifications, the written and the unwritten ones. You must anticipate a large number of influences, like temperature effects, supply voltages changes, offset voltages, layout parasitics, and numerous kinds of technology variations to end up with a circuit that works. This is challenging for analog, custom-digital, mixed-signal or RF circuits, and often researching new design methods in relevant journals, conference proceedings and design tools unfortunately gives the impression that just a "wild bunch" of "advanced techniques" exist. On the other hand, state-of-the-art tools nowadays indeed offer a good cockpit to steer the design flow, which include clever statistical methods and optimization techniques.Actually, this almost presents a second breakthrough, like the introduction of circuit simulators 40 years ago! Users can now conveniently analyse all the problems (discover, quantify, verify), and even exploit them, for example for optimization purposes. Most designers are caught up on everyday problems, so we fit that "wild bunch" into a systematic approach for variation-aware design, a designer''s field guide and more. That is where this book can help! Circuit Design: Anticipate, Analyze, Exploit Variations starts with best-practise manual methods and links them tightly to up-to-date automation algorithms. We provide many tractable examples and explain key techniques you have to know. We then enable you to select and setup suitable methods for each design task - knowing their prerequisites, advantages and, as too often overlooked, their limitations as well. The good thing with computers is that you yourself can often verify amazing things with little effort, and you can use software not only to your direct advantage in solving a specific problem, but also for becoming a better skilled, more experienced engineer. Unfortunately, EDA design environments are not good at all to learn about advanced numerics. So with this book we also provide two apps for learning about statistic and optimization directly with circuit-related examples, and in real-time so without the long simulation times. This helps to develop a healthy statistical gut feeling for circuit design. The book is written for engineers, students in engineering and CAD / methodology experts. Readers should have some background in standard design techniques like entering a design in a schematic capture and simulating it, and also know about major technology aspects.

DKK 363.00
1