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Chromosome Architecture - - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Chromosome Architecture - - Bog - Springer-Verlag New York Inc. - Plusbog.dk

This detailed new edition collects cutting-edge laboratory protocols, techniques, and applications in use by some of the leading international experts in the broad field of chromosome architecture. The book emphasizes the increasing physiological relevance of chromosome architecture investigation, manifest both through application of more complex bottom-up assays in vitro as well as through maintaining the native physiological context through the investigation of living, functional cells. In addition, the chapters reflect the dramatic improvement in the length scale of precision by utilizing single-molecule approaches, both for imaging the DNA content of chromosome and proteins that bind to DNA as well as using methods that can controllably manipulate single DNA molecules, and the use of advanced computational methods and mathematical analysis is also featured. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Chromosome Architecture: Methods and Protocols, Second Edition is an ideal guide for researchers working in this dynamic area of study.

DKK 986.00
2

Strategy and Architecture of Health Care Information Systems - Michael K. Bourke - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Strategy and Architecture of Health Care Information Systems - Michael K. Bourke - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Information technology constantly changes and quickly becomes obsolete. The methodology of planning and implementing a health care information system, however, is more constant. Through practical, step-by-step guidelines, the author demonstrates how to establish the strategy and architecture against which vendor and system decisions must be made. Both management and technical perspectives are discussed. Thus, regardless of the technology used, the health care administrator and systems manager learn to implement information systems successfully and to link those systems with business strategy to achieve higher quality and more cost-effective patient care.

DKK 434.00
4

The Bone Book - Sumon Nandi - Bog - Springer-Verlag New York Inc. - Plusbog.dk

The Bone Book - Sumon Nandi - Bog - Springer-Verlag New York Inc. - Plusbog.dk

The Bone Book: An Orthopedic Manual is a complete guide to the essentials of orthopedics in today''s busy hospital setting. Concise chapters provide the basic knowledge that all orthopedic surgery residents, fellows, and supporting staff must know to handle the full range of conditions, injuries, and diseases for patients in the operating and emergency room settings. Included are essentials of musculoskeletal anatomy, physical examination, orthopedic emergencies, and ER consults, including care for fractures, dislocations, bone/joint infections, and spinal cord injuries. Additional chapters cover OR basics, such as patient positioning, prepping, and draping, and common orthopedic techniques, such as splinting, joint aspiration, and regional blocks. By compiling information commonly passed down from senior to junior surgeon, the authors have distilled a wide range of orthopedic fundamentals into one easy-to-read book.

DKK 634.00
4

The Little Book of Bigger Primes - Paulo Ribenboim - Bog - Springer-Verlag New York Inc. - Plusbog.dk

The Little Book of Bigger Primes - Paulo Ribenboim - Bog - Springer-Verlag New York Inc. - Plusbog.dk

A deep understanding of prime numbers is one of the great challenges in mathematics. In this new edition, fundamental theorems, challenging open problems, and the most recent computational records are presented in a language without secrets. The impressive wealth of material and references will make this book a favorite companion and a source of inspiration to all readers. Paulo Ribenboim is Professor Emeritus at Queen''s University in Canada, Fellow of the Royal Society of Canada, and recipient of the George Pólya Award of the Mathematical Association of America. He is the author of 13 books and more than 150 research articles. From the reviews of the First Edition: Number Theory and mathematics as a whole will benefit from having such an accessible book exposing advanced material. There is no question that this book will succeed in exciting many new people to the beauty and fascination of prime numbers, and will probably bring more young people to research in these areas. ( Andrew Granville, Zentralblatt )

DKK 434.00
4

First Steps in Differential Geometry - Andrew Mcinerney - Bog - Springer-Verlag New York Inc. - Plusbog.dk

First Steps in Differential Geometry - Andrew Mcinerney - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Differential geometry arguably offers the smoothest transition from the standard university mathematics sequence of the first four semesters in calculus, linear algebra, and differential equations to the higher levels of abstraction and proof encountered at the upper division by mathematics majors. Today it is possible to describe differential geometry as "the study of structures on the tangent space," and this text develops this point of view. This book, unlike other introductory texts in differential geometry, develops the architecture necessary to introduce symplectic and contact geometry alongside its Riemannian cousin. The main goal of this book is to bring the undergraduate student who already has a solid foundation in the standard mathematics curriculum into contact with the beauty of higher mathematics. In particular, the presentation here emphasizes the consequences of a definition and the careful use of examples and constructions in order to explore those consequences.

DKK 510.00
2

The Book of Genes and Genomes - Susanne B. Haga - Bog - Springer-Verlag New York Inc. - Plusbog.dk

The Book of Genes and Genomes - Susanne B. Haga - Bog - Springer-Verlag New York Inc. - Plusbog.dk

The Book of Genes & Genomes presents a concise overview of the advances in genetics and genomics and provides the unfamiliar reader with a succinct description of many of the applications and implications of this field. Given the substantial investment in genetics and genomics over the past several decades and the many recent discoveries and developments, this book will help the reader begin to understand the importance of genetics and genomics to us all. This exciting new title includes information on how genetics and genomics has advanced our understanding of health and medicine, evolution, and biology, as well as how they are pushing the boundaries of ethics and social values. - Assumes no prior knowledge on the part of the reader; - Easy to understand writing style, enabling novices to read and speak the "language" of genes and genomes; - Inclusion of case-studies that depict how genes and genomics have advanced understanding of health,medicine, evolution and biology, but juxtaposed to ethics and social values; - Recommended reading offered to facilitate self study; - Clear, up to date and affordable.

DKK 260.00
2

The Jewelry Design Source Book - Patricia Bayer - Bog - Springer-Verlag New York Inc. - Plusbog.dk

The Jewelry Design Source Book - Patricia Bayer - Bog - Springer-Verlag New York Inc. - Plusbog.dk

ofp:HII..''rn book-; published from the 16th to the 19th cen· lUrks. while practical expenise emigrated with lluguenot nali:-;men alkr the !{evocation of the Edict of Nantes in 16H''). Other jewelers were invited to work at the reign rulers, and visiting ladies took advantage of their time in Paris to have their jewels rt''set. Although the French Revolution of 17H9 brought this luxwy trade to a standstill, it was triumphantly revived under Napoleon. Even the collapse of the Second Empire in I H70 could not shake it. ·n,e great dynasties of Canit:r, limu:heron, and Chaumet survi\"lxl the disaster unscathed and expanded their empires into the 20th century, setting up branches in Lon· don. New York. Switzerland, and japan. It was from Paris, too, that the pioneers of Art Nouveau and An Deco emerged to generate the ideas which the great jewelers then tr~msf(nned into r:tshionahle jewels. A-; ;I rt:Slllt of the close connection between the leading jewelers and cou· ture houses. designs have been conceived in harmony with the latestl:tshions in dress; this has contributed to the continuingsuccessofthe French firms in the.post·Second World War peri

DKK 663.00
1

Hi-C Data Analysis - - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Hi-C Data Analysis - - Bog - Springer-Verlag New York Inc. - Plusbog.dk

This volume details a comprehensive set of methods and tools for Hi-C data processing, analysis, and interpretation. Chapters cover applications of Hi-C to address a variety of biological problems, with a specific focus on state-of-the-art computational procedures adopted for the data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Hi-C Data Analysis: Methods and Protocols aims to help computational and molecular biologists working in the field of chromatin 3D architecture and transcription regulation.

DKK 986.00
2

Stem Cell Transcriptional Networks - - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Stem Cell Transcriptional Networks - - Bog - Springer-Verlag New York Inc. - Plusbog.dk

This second edition provides techniques used to study of the underlying transcriptional programs of stem cells that promote self-renewal and differentiation. Chapters detail next-generation sequencing technologies, data analysis, protocols on analysis and visualization of single-cell RNA-Seq data, analysis of 3D chromatin architecture, interpretation of large-scale interaction networks, transcriptional networks in embryonic and adult stem cells, derivation of stem cells, and transcriptional programs that promote reprogramming, transdifferentiation, and cancer formation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Stem Cell Transcriptional Network: Methods and Protocols, Second Edition aims to provide a key resource for biologists seeking to interrogate these vital networks.

DKK 967.00
4

Counter-Terrorism Policing - Jude Mcculloch - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Counter-Terrorism Policing - Jude Mcculloch - Bog - Springer-Verlag New York Inc. - Plusbog.dk

This book sets out to examine the impact of terrorism on the policing organisation and culturally diverse communities. It is the first book of its kind to contextualise counter-terrorism policing in a conceptual framework and takes account of the unique challenge of the increasing cosmopolitan character of major cities. Based on detailed documentary and ethnographic research, this relevant book holds significant lessons for cosmopolitan cities around the world.

DKK 816.00
4

Counter-Terrorism Policing - Jude Mcculloch - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Counter-Terrorism Policing - Jude Mcculloch - Bog - Springer-Verlag New York Inc. - Plusbog.dk

This book sets out to examine the impact of terrorism on the policing organisation and culturally diverse communities. It is the first book of its kind to contextualise counter-terrorism policing in a conceptual framework and takes account of the unique challenge of the increasing cosmopolitan character of major cities. Based on detailed documentary and ethnographic research, this relevant book holds significant lessons for cosmopolitan cities around the world.

DKK 816.00
4

Regional Stratigraphy of North America - D.r. Schwimmer - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Regional Stratigraphy of North America - D.r. Schwimmer - Bog - Springer-Verlag New York Inc. - Plusbog.dk

An early reviewer of this book stated that he had difficulty assessing its marketability because it "falls between the cracks" of geological literature. We have designed this book to meet a need of modem geology: namely, a single source providing both detailed and synoptic stratigraphy of the various regions of North America, through geological time. Shortly after beginning work on such a book, we realized why it had not yet been written: it required six years of effort, assimilation of an incredible amount of information, and two years'' additional work to cut the volume down to publishable size. Further, by the time the final chapter was written, the fIrst few were already out of date. Nevertheless, the book lies in front of you. It is intended to serve several purposes. As a textbook, it will serve the following courses: • Regional stratigraphy • Sedimentary tectonics • Regional tectonics • Advanced historical geology • Survey-level paleontology Obviously, not all portions of the book are relevant to all of the above courses. We assume the reader will retain this book after the particular course is done, and will use it as a reference book. Hopefully, others will obtain the book solely for reference purposes. We believe it will be especially useful for the working geologist or academic geologist seeking generalized and some moderately detailed information about a region or geological time interval which is unfamiliar.

DKK 663.00
1

Advanced Computer Graphics - - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Advanced Computer Graphics - - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Computer graphics is no longer merely a technique of promise. The case studies in this book prove that it is a technique which has already identified itself with progress in an astonishingly wide range of app­ lications, to the extent that it has been necessary to group many chapters into sections dealing with specific categories, such as the design of electrical circuits, civil engineering, architecture, nuclear and space science and text editing. In the last couple of years, computer graphics has blossomed out from the stage in which it was confined almost exclusively to the large scale industries of aircraft and automobile engineering. It has also developed additional advantages, mote than the simple idea of doing the same thing more quickly. Now the technique offers entirely new ways of doing old things, with consequent greater efficiency and accuracy; and it also brings a way of doing new things, which were previously not possible. In the introduction to their paper in Part 12, Armit and Forrest state: "We do not discuss those systems which are merely computer versions of existing design methods, but rather those systems which make use of techniques for design which are beyond the possibilities of conventional drafting." Similarly, Ranaweer3; and Leckie end their paper in Part 4 with the comment: "Thus the man and the machine can work as a team to arrive at a solution better than that which can be arrived at by either one alone".

DKK 663.00
1