An anti-hyperglycemic molecule, RNF01 - Joharinera Rakotobe

This book was written to study the antihyperglycaemic activity of the RFN01 extract in mice. In vivo tests were performed in mice made hyperglycaemic after glucose overload (2 g/kg, per os) and by alloxane injection (150 mg/kg, i.p.). RNF01 reduced the transient hyperglycaemia induced by glucose overload to 6.85 ± 0.24 mmol/l and 5.95 ± 0.62 mmol/l at 400 mg/kg and 500 mg/kg compared to the control which was 8.85 ± 0.62 mmol/l (p