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Radiopharmaceuticals and Brain Pathophysiology Studied with Pet and Spect

Radiopharmaceuticals and Brain Pathophysiology Studied with Pet and Spect

First published in 1991 this book covers three major areas essential to in vivo biochemical studies with PET and SPECT: synthesis of radiopharmaceuticals biological modeling and clinical applications. The book emphasizes advances in the synthesis of radiopharmaceuticals used in PET and SPECT studies of brain flow and oxidatative metabolism in addition to biological modeling. The most widely used 2-deoxyglucose/2-fluorodeoxyglucose models are discussed as well as models used in the quantitation of brain receptors. Other topics include a possible model for converting 6-[18F] fluorodopa images into the quantitative rate of dopamine synthesis evaluations of technetium- and iodine-labeled blood flow tracers and possibilities for using SPECT to measure other pathophysiological variables. This book will be a valuable reference source to students and specialists interested in these in vivo measurements. | Radiopharmaceuticals and Brain Pathophysiology Studied with Pet and Spect

GBP 36.99
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Therapeutic Interventions in Three Sentences Reshaping Ericksonian Hypnotherapy by Talking to the Brain and Body

Therapeutic Interventions in Three Sentences Reshaping Ericksonian Hypnotherapy by Talking to the Brain and Body

Following tenets set out by Milton Erickson Therapeutic Interventions in Three Sentences: Reshaping Ericksonian Hypnotherapy by Talking to the Brain and Body presents an array of short effective commands which have been developed for use in connection with a wide range of mental and psychosomatic disorders. Examining in detail the basic building blocks which must be in place in order for someone to send an effective command to his or her sub-conscious mind the book presents an elegant way of using informal variations of Ericksonian hypnotherapy in awake states and transferring these principles to a variety of therapeutic settings. The methods described follow specific rules derived from hypnotherapy but can be integrated into any other form of counselling or therapy and can be used in short sessions in telephone consultations and with patients in critical states as well as conversations of a therapeutic nature by non-therapeutic professionals. The book explains why and how these interventions work their general structure and how they can be used to tackle specific needs such as trauma depression and anxiety disorders. The book will be of great interest to counsellors doctors and therapists of different orientations who are looking for therapeutic methods that can be used in short sessions or with patients in critical states as well as non-therapeutic professionals who engage in conversations of a therapeutic nature such as social workers pastors nurses carers and teachers (including SEN teachers). | Therapeutic Interventions in Three Sentences Reshaping Ericksonian Hypnotherapy by Talking to the Brain and Body

GBP 18.99
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The Blood-Cerebrospinal Fluid Barrier

The Blood-Cerebrospinal Fluid Barrier

Despite the existence of two barrier systems in the brain research over the last century has mostly focused on the blood-brain barrier rather than on the blood-CSF barrier. Today there is a greater understanding of the function of the blood-CSF barrier and of the choroid plexus a tissue that is the primary site of this barrier. With the growing number of studies that focus on the role of the blood-CSF barrier in CNS homeostasis and neurological disorders a modern overview of the blood-CSF barrier is long overdue. The Blood-Cerebrospinal Fluid Barrier is exclusively devoted to the blood-CSF barrier. Internationally renowned experts discuss the most recent progress in the field of choroid plexus physiology and update our knowledge of the function of the blood-CSF barrier. The book begins with an overview of the development and morphology of the choroid plexus and then covers various aspects of its function such as the regulation of choroidal blood flow ion transport and the production and transport of polypeptides. Following an extensive section on the role of the choroid plexus in CNS disorders the final section discusses in vitro in vivo and in situ models of the blood-CSF barrier. This unique book analyzes a wealth of new research on the proven and potential roles of the choroid plexus/blood-CSF barrier in the brain. It is a valuable resource that will foster future studies in neuroscience pharmacology and toxicology.

GBP 39.99
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Dopamine Endocrine and Oncogenic Functions

Dopamine Endocrine and Oncogenic Functions

Dopamine is a small molecule traditionally regarded as a brain-derived neuronal modulator implicated in many neurological and psychiatric disorders. Outside the brain dopamine fulfills all the criteria of a circulating hormone which affects normal and abnormal functions of multiple organs and regulatory systems and is also involved in many aspects of cancer formation and progression. This book provides a much needed systematic account of dopamine as an endocrine and autocrine/paracrine hormone and fills a major gap in the overall understanding of the production distribution and actions of this very important molecule. Key Features:Explores the many different faces of dopamine as autocrine paracrine and endocrine moleculeDocuments the adverse effects of antipsychotics on dopamine functionsReviews the many ways dopamine affects the cardiovascular renal and reproductive systemsProvides updates on receptor oligomerization and signalingExamines the role of dopamine in tumorigenesisRelated TitlesJones S. ed. Dopamine - Glutamate Interactions in the Basal Ganglia (ISBN 978-0-3673-8197-4)Luo L. Principles of Neurobiology (ISBN 978-0-8153-4494-0)Sidhu A. et al. eds. Dopamine Receptors and Transporters (ISBN 978-0-8247-0854-2) | Dopamine Endocrine and Oncogenic Functions

GBP 42.99
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Making Sense of the EEG From Basic Principles to Clinical Applications

Making Sense of the EEG From Basic Principles to Clinical Applications

This book educates the reader on the cellular and neurophysiological aspects of Electroencephalography (EEG) alongside its technical and engineering principles. Providing a background on normal EEG the content includes the clinical applications of EEG in epilepsies and other brain disorders in order to provide the reader with the necessary knowledge to use EEG in clinical practice. Aimed at those who in the earlier stages of using EEGs this resource provides an effective overview and offers a key resource to anyone using EEGs. | Making Sense of the EEG From Basic Principles to Clinical Applications

GBP 39.99
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Game Dev Stories Volume 2 More Interviews About Game Development and Culture

Game Dev Stories Volume 2 More Interviews About Game Development and Culture

Game Dev Stories: Interviews About Game Development and Culture Volumes 1 and 2 are a collection of interviews from renowned author David L. Craddock as he explores all corners of the video game industry. Collected from the author's archives Game Dev Stories gathers conversations with individuals from all corners of the industry: Who they are the paths they paved and their contributions to this multibillion-dollar industry. This text offers viewpoints from well-known individuals like John Romero Tom Hall and Matt Householder. From artists and writers to programmers and designers Game Dev Stories offers amazing insights and understanding to what occurs behind the screens of your favorite games and may help inspire future game developers in pursuing their dreams. Author Bio David L. Craddock writes fiction nonfiction and grocery lists. He is the author of over a dozen nonfiction books about video game development and culture including the bestselling Stay Awhile and Listen series Arcade Perfect: How Pac-Man Mortal Kombat and Other Coin-Op Classics Invaded the Living Room and fiction for young adults including The Dumpster Club and Heritage: Book One of the Gairden Chronicles. Find him online @davidlcraddock on Twitter. | Game Dev Stories Volume 2 More Interviews About Game Development and Culture

GBP 38.99
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Atlas of Alzheimer's Disease

Atlas of Alzheimer's Disease

The last 20 years have brought unprecedented new knowledge to our understanding of Alzheimer's disease (AD) and for the first time approved symptomatic treatments. Authored by one of the world's leading authorities on the management of AD and related dementias this highly illustrated Atlas of Alzheimer’s Disease describes the colorful history of the illness its neuropathological basis from structural brain imaging and post-mortem studies and its devastating effects on perception cognition communication and social behavior. In addition to an accurate and detailed historical perspective the book provides a state-of-the-art review of current working hypotheses diagnostic approaches and treatments of AD. Many tables and illustrations help readers comprehend the scientific information provided and the book places great emphasis on the increasingly identifiable risk factors for development of the disease with a view towards prevention. | Atlas of Alzheimer's Disease

GBP 39.99
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The Road to Einstein's Relativity Following in the Footsteps of the Giants

The Road to Einstein's Relativity Following in the Footsteps of the Giants

CHOICE Highly Recommended Title August 2019 Expertly guided by renowned cosmologist Dr. David Lyth learn about the pioneering scientists whose work provided the foundation for Einstein’s formulation of his theories of relativity and about Einstein's groundbreaking life and work as well. This highly readable and accessible panorama of the field delicately balances history and science as it takes the reader on an adventure through the centuries. Without complex mathematics or scientific formulae this book will be of interest to all even those without a scientific background who are intrigued to find out more about what paved the way for one of our most famous physicists to push the boundaries of physics to new lengths. Features: Written by an internationally renowned physicist and cosmologist Describes the life and times of Einstein and his important predecessors Focuses on one of the most famous areas of science Einstein’s Relativity Theory | The Road to Einstein's Relativity Following in the Footsteps of the Giants

GBP 24.99
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Beyond Menopause New Pathways to Holistic Health

Beyond Menopause New Pathways to Holistic Health

Beyond Menopause uncovers the unique healthcare needs of postmenopausal women. It offers women integrative holistic approaches that bridge the gap between conventional medicine and systems of holistic healing. The book highlights integrative strategies in the context of common health conditions including anxiety fatigue sleep disturbance sexual health weight concerns bone health and brain health. It provides information on the use of hormone therapy during the menopause transition. The book features clinical vignettes illustrating how individual women explore pathways to better health through shared decision-making with their health practitioners. Women of postmenopausal age want to remain healthy vital and engaged yet they are often overlooked in the healthcare system. In this phase of life women need to create their own integrative path to wellness. Beyond Menopause shows women how to prime their voice for self-advocacy and establish collaborative relationships with their health practitioners. Women are advised to create an adaptable network of practitioners to accommodate changing needs—their own “web of wellness. ” Beyond Menopause brings a fresh perspective to the mental physical and spiritual elements of holistic living. From the distinct vantage points of medicine and neuroscience the authors guide women toward new pathways to optimal health and well-being. | Beyond Menopause New Pathways to Holistic Health

GBP 19.99
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Drugs That Changed the World How Therapeutic Agents Shaped Our Lives

Drugs That Changed the World How Therapeutic Agents Shaped Our Lives

Drugs are used in the diagnosis alleviation treatment prevention or cure of disease. This is a book about drugs how they came to be and how they exert their ‘magic’. Today we have drugs to protect against infectious diseases to alleviate aches and pains to allow new organs to replace the old and for brain functions to be modified. Yet for the most part the manner by which drugs are developed and by whom remains a mystery. Drugs are more than just a pill or liquid and some have markedly altered history. The author has selected a few drugs – highlights representing milestones affecting our well-being and influencers of social change. The stories told are dramatic and include spectacular successes and dismal failures. And the people about whom these stories are told are both saints and sinners – selfless and conniving – bold and mercurial and shy and retiring loner. The drugs themselves mirror the diversity of their origin stories and the author assembles all sides of these fascinating stories. Key Selling Features: Chronicles the development of some of the most significant drugs affecting human health Offers easy-to-follow and understandable explanations of how drugs work Explains the science underlying the processes of drug discovery Helps readers appreciate the contributions of the individuals involved in drug discovery and development Serves as essential reading for anyone interested in human health and public policy | Drugs That Changed the World How Therapeutic Agents Shaped Our Lives

GBP 27.99
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One-Week Dungeons Diaries of a Seven-Day Roguelike Challenge

One-Week Dungeons Diaries of a Seven-Day Roguelike Challenge

An entertaining race-against-time narrative. —Kobo review A fast-paced look into seven-day roguelikes something so niche most people wouldn't have heard about but the book is well written and shows how important it is to get your thoughts down so you can sort out your ideas. —Goodreads review Eleven game designers. Eight grand ideas. Seven days to will them into reality. Every year programmers around the world compete in the 7-day roguelike challenge or 7DRL a weeklong game jam where participants endeavor to design and program a roguelike role-playing game. Their obstacles: day jobs family responsibilities sleep deprivation and visionary concepts too big for 168 hours to contain. Told over a series of daily journal logs One-Week Dungeons: Diaries of a Seven-Day Roguelike Challenge chronicles the journeys of eleven 7DRL participants as they race to build their dream games before the clock expires. David L. Craddock writes fiction nonfiction and grocery lists. He is the author of over a dozen nonfiction books about video game development and culture including the bestselling Stay Awhile and Listen series and Arcade Perfect: How Pac-Man Mortal Kombat and Other Coin-Op Classics Invaded the Living Room and fiction for young adults including The Dumpster Club and Heritage: Book One of the Gairden Chronicles. Find him online @davidlcraddock on Twitter. | One-Week Dungeons Diaries of a Seven-Day Roguelike Challenge

GBP 28.99
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Integrating Lifestyle Medicine in Cardiovascular Health and Disease Prevention

Integrating Lifestyle Medicine in Cardiovascular Health and Disease Prevention

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the United States and around the world. Major risk factors for CVD result from poor lifestyle habits and practices but the area of lifestyle medicine has emerged to help clinicians and their patients understand the power of positive lifestyle habits and actions. Written by cardiologist and lifestyle medicine pioneer Dr. James Rippe Integrating Lifestyle Medicine in Cardiovascular Health and Disease Prevention introduces the principles of lifestyle medicine with the practice of cardiology to help lower the risk of heart disease and if already present assist in its treatment. This book provides evidence-based information on both the prevention and treatment of CVD through lifestyle measures such as regular physical activity sound nutrition weight management and avoidance of tobacco products. This information aids physicians and patients to better understand multiple linkages between poor habits and practices employing them with associated behavioral techniques to lessen the likelihood of developing CVD. Features: Summarizes major issues in CVD including heart attack stroke atrial fibrillation high blood pressure lipid abnormalities and obesity. Provides protocols for overcoming a sedentary lifestyle and using lifestyle medicine techniques to optimize brain health. Empowers clinicians with vital information for consultations on the power of lifestyle medicine practices both to treat symptoms if already present or to prevent major components of CVD from developing in the future. Written for practitioners at all levels this user-friendly volume in the Lifestyle Medicine series is valuable to practitioners in general medicine or subspecialty practices including lifestyle medicine and cardiology.

GBP 42.99
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RNA the Epicenter of Genetic Information

RNA the Epicenter of Genetic Information

The origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history. This book documents the many advances as well as the prejudices and founder fallacies. It highlights the premature relegation of RNA to simply an intermediate between gene and protein the underestimation of the amount of information required to program the development of multicellular organisms and the dawning realization that RNA is the cornerstone of cell biology development brain function and probably evolution itself. Key personalities their hubris as well as prescient predictions are richly illustrated with quotes archival material photographs diagrams and references to bring the people ideas and discoveries to life from the conceptual cradles of molecular biology to the current revolution in the understanding of genetic information. Key Features Documents the confused early history of DNA RNA and proteins - a transformative history of molecular biology like no other. Integrates the influences of biochemistry and genetics on the landscape of molecular biology. Chronicles the important discoveries preconceptions and misconceptions that retarded or misdirected progress. Highlights major pioneers and contributors to molecular biology with a focus on RNA and noncoding DNA. Summarizes the mounting evidence for the central roles of non-protein-coding RNA in cell and developmental biology. Provides a thought-provoking retrospective and forward-looking perspective for advanced students and professional researchers. The Open Access version of this book available at www. taylorfrancis. com has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4. 0 license. | RNA the Epicenter of Genetic Information

GBP 39.99
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The Junior Medical Officer's Guide to the Hospital Universe A Survival Manual

The Junior Medical Officer's Guide to the Hospital Universe A Survival Manual

something special out-of-the-ordinary … I wish I had had a manual like this one at that stage of my career. I would have found the multitude of templates and lists a godsend … an accessible entertaining work about ‘life in medicine’. Professor David Bennett AO Adolescent Health Physician Developmental Paediatrics Sydney Australia As a doctor who has recently completed her internship on reflection there are so many things I wish I knew before starting. The author has done an exceptional job in providing a great summary of advice to assist JMOs survive their first years in the hospital which is very relevant to their day-to-day work. The writing style is relatable and makes for an easy-to-read book which is also comical at times. Dr Mitsi Blazos Basic Physician Trainee The Alfred Hospital Melbourne Australia The JMO Years… Insane Hours. Endless patients. Mountains of paperwork. Inexorable pressure. Interminable years of training. No life outside work. How will you get the job done well? How will you survive? Look no further. This is the essential guide to the real life of and in the hospital. Providing invaluable guidance throughout with this book as your companion you will be able to clear those discharges get those consults survive after hours get your work-life balance in order and ultimately be the doctor you really want to be. Addressing every facet of the JMO’s true role the book enables and supports junior doctors and medical students to thrive in their new position within the hospital system aiding the streamlined completion of administration maximising efficiency with no compromise in accuracy all with the final objective of ensuring the best possible outcome for patients while maintaining the health function and happiness of the health care provider. | The Junior Medical Officer's Guide to the Hospital Universe A Survival Manual

GBP 26.99
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Mechatronics and Robotics New Trends and Challenges

Mechatronics and Robotics New Trends and Challenges

The term “mechatronics” was coined in 1969 merging “mecha” from mechanism and “tronics” from electronics to reflect the original idea at the basis of this discipline that is the integration of electrical and mechanical systems into a single device. The spread of this term and of mechatronics itself has been growing in the years including new aspects and disciplines like control engineering computer engineering and communication/information engineering. Nowadays mechatronics has a well-defined and fundamental role in strict relation with robotics. Drawing a sharp border between mechatronics and robotics is impossible as they share many technologies and objectives. Advanced robots could be defined as mechatronic devices equipped with a “smart brain” but there are also up-to-date mechatronic devices used in tight interaction with humans that are governed by smart architectures (for example for safety purposes). Aim of this book is to offer a wide overview of new research trends and challenges for both mechatronics and robotics through the contribution of researchers from different institutions providing their view on specific subjects they consider as “hot topics” in both fields with attention to new fields of application new challenges to the research communities and new technologies available. The reader of this book will enjoy the various contributions as they have been prepared with actual applications in mind along a journey from advanced actuators and sensors to human-robot interaction through robot control navigation planning and programming issues. The book presents several state-of-the-art solutions like multiple-stage actuation to cope with conflicting specification of large motion-spans ultra-high accuracy model-based control for high-tech mechatronic systems modern approaches of software systems engineering to robotics aand humanoids for human assistance. The reader can also find new techniques in approaching the design of mechatronic systems in some possible industrial and service robotics scenarios with a particular attention for the interaction between humans and mechanisms. | Mechatronics and Robotics New Trends and Challenges

GBP 39.99
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