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Corticotropin-Releasing Factor Basic and Clinical Studies of a Neuropeptide

Corticotropin-Releasing Factor Basic and Clinical Studies of a Neuropeptide

This book provides a comprehensive summary of data from basic and clinical studies in support of a role for corticotropin-releasing factor (CRF) as a neurotransmitter in the mammalian central nervous system (CNS). It includes descriptions of the anatomy of CRF and its receptors in the CNS as well as the characterization of CRF receptors and the second messenger systems mediating effects of CRF in the brain. It discusses the autonomic behavioral and electrophysiologic effects of CRF administration in the brain. This work also includes a section which covers the role of brain CRF in the etiology and pathophysiology of a variety of neurologic psychiatric and endocrine disorders. Endocrinologists brain researchers and neuroendocrinologists are among those who will find this reference both useful and interesting. | Corticotropin-Releasing Factor Basic and Clinical Studies of a Neuropeptide

GBP 205.00
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Problem Solving for Engineers

Problem Solving for Engineers

Whatever their discipline engineers are routinely called upon to develop solutions to all kinds of problems. To do so effectively they need a systematic and disciplined approach that considers a range of alternatives taking into account all relevant factors before selecting the best solution. In Problem Solving for Engineers David Carmichael demonstrates just such an approach involving problem definition generation of alternative solutions and ultimately the analysis and selection of a preferred solution. David Carmichael introduces the fundamental concepts needed to think systematically and undertake methodical problem solving. He argues that the most rational way to develop a framework for problem solving is by using a systems studies viewpoint. He then outlines systems methodology modeling and the various configurations for analysis synthesis and investigation. Building on this the book details a systematic process for problem solving and demonstrates how problem solving and decision making lie within a systems synthesis configuration. Carefully designed as a self-learning resource the book contains exercises throughout that reinforce the material and encourage readers to think and apply the concepts. It covers decision making in the presence of uncertainty and multiple criteria including that involving sustainability with its blend of economic social and environmental considerations. It also characterizes and tackles the specific problem solving of management planning and design. The book provides for the first time a rational framework for problem solving with an engineering orientation.

GBP 180.00
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