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The Microbiome and the Brain

The Microbiome and the Brain

Brain related disorders are among the most challenging health issues of our time. The development of effective therapeutic and preventive strategies for these disorders relies on a comprehensive understanding of the underlying causative mechanisms. And until recently these mechanisms have remained somewhat elusive. The newly discovered pivotal role of the intestinal microbiome in brain health functionality and resistance to disease is revolutionizing neuroscience. The Microbiome and the Brain through the contributions of some of the most forward thinking researchers and clinicians in the field comprehensively reveals the leading edge of our understanding of the fundamental role of gut microbes and their metabolites in a wide array of seemingly diverse brain issues including Alzheimer’s disease autism multiple sclerosis and mood disorders. In addition mechanisms defining these relationships are explored along with a presentation of the state-of-the-art as it relates to interpretation of relevant laboratory assessments. Finally novel therapeutic opportunities derived from this exciting science are presented. Readers will learn:The highly validated relationship between alterations of gut microbes and their metabolites and risk for Alzheimer’s disease. The important link between autism and intestinal dysbiosis. Appropriate interpretation of available laboratory assessments of the intestinal microbiome. The potential role of fecal microbial transplant in neurological diseases. The influence of diet and other lifestyle choices on the microbiome as it relates to brain health and functionality.

GBP 44.99
1

Ethanol and the Liver Mechanisms and Management

The Economics of International Trade and the Environment

The Economics of International Trade and the Environment

Issues related to environmental protection and trade liberalization have moved to the forefront of international policy agendas. The Economics of International Trade and the Environment explores - from an economic standpoint - many of the questions that are germane in increasing our knowledge of environmental policy in the presence of international trade and trade policy in the presence of environmental externalities. Ultimately we must ask What can economic theory tell us about the connections between environmental and trade policy? This book uses the tools of game and microeconomic theory to analyze diverse issues such as: the effects of international trade in waste products on illegal disposal the nature of environmental policy when market structure and plant locations are endogenous and the issue of ecological dumping. The authors apply economic theory to practical settings to ascertain the extent to which this theory can inform policy decisions about problems at the interface of international trade and the environment. Edited by well-known researchers and authors this is the only resource that can serve as an effective guide to the theoretical and empirical literature on international trade and the environment. The Economics of International Trade and the Environment provides comprehensive coverage on a wide variety of topics and contains the most recent contributions in this area and is suitable as a graduate course in Economics and International Trade

GBP 59.99
1

Biosecurity in the Making The Threats the Aspects and the Challenge of Readiness

Elementary Particles and the Early Universe A Synergy of Particle Physics and Cosmology in the Birth and Evolution of the Universe

Elementary Particles and the Early Universe A Synergy of Particle Physics and Cosmology in the Birth and Evolution of the Universe

The birth of the Universe and its subsequent evolution is an exciting blend of Cosmology Particle Physics and Thermodynamics. This book with its synoptic approach provides an accessible introduction to these fascinating topics. It begins in Part I with an overview of cosmology and is followed by a discussion on the present understanding about the birth of the universe detailing the Planck Era Inflation and the Big Bang. It speculates the possibility of multiple universes. Before moving on to explore the essentials of the Standard Model of Particle Physics in Part II with particular stress on the electroweak force the first example of acquisition of mass by gauge bosons via the Higgs mechanism. The book finishes in Part III with the thermal history of the Universe. This will also lead to understanding baryonic matter and baryogenesis as well as nucleosynthesis This book is suitable for those taking courses on particle physics general relativity and cosmology. Readers mathematically inclined who wish to enhance their basic knowledge about the early Universe will also find this book suitable to move up to the next level. Features: Authored by experienced lecturers in Particle Physics Quantum Field Theory Nuclear Physics and General Relativity Provides an accessible introduction to Particle Physics and Cosmology | Elementary Particles and the Early Universe A Synergy of Particle Physics and Cosmology in the Birth and Evolution of the Universe

GBP 44.99
1

The Standard Model and Beyond

The Standard Model and Beyond

This new edition of The Standard Model and Beyond presents an advanced introduction to the physics and formalism of the standard model and other non-abelian gauge theories. It provides a solid background for understanding supersymmetry string theory extra dimensions dynamical symmetry breaking and cosmology. In addition to updating all of the experimental and phenomenological results from the first edition it contains a new chapter on collider physics; expanded discussions of Higgs neutrino and dark matter physics; and many new problems. The book first reviews calculational techniques in field theory and the status of quantum electrodynamics. It then focuses on global and local symmetries and the construction of non-abelian gauge theories. The structure and tests of quantum chromodynamics collider physics the electroweak interactions and theory and the physics of neutrino mass and mixing are thoroughly explored. The final chapter discusses the motivations for extending the standard model and examines supersymmetry extended gauge groups and grand unification. Thoroughly covering gauge field theories symmetries and topics beyond the standard model this text equips readers with the tools to understand the structure and phenomenological consequences of the standard model to construct extensions and to perform calculations at tree level. It establishes the necessary background for readers to carry out more advanced research in particle physics. Supplementary materials are provided on the author’s website and a solutions manual is available for qualifying instructors.

GBP 44.99
1

Nutrition and the Developing Brain

Comparative Anatomy of the Mouse and the Rat A Color Atlas and Text

Energy the Environment and Sustainability

The New Cosmic Onion Quarks and the Nature of the Universe

Endocannabinoids The Brain and Body's Marijuana and Beyond

Endocannabinoids The Brain and Body's Marijuana and Beyond

Over the past decade there have been major advances in understanding the mechanisms whereby marijuana interacts with the brain in producing psychoactive and potentially therapeutic effects. The discovery of specific gene coding for cannabinoid receptors activated by smoking marijuana and the finding of endogenous cannabinoids which also activate the receptors have transformed cannabinoid research into mainstream science with significant implications in human health and disease Endocannabinoids: The Brain and Body’s Marijuana and Beyond documentsadvances in the discovery and functioning of naturally occurring marijuana-like substances in human biology. It explores recent findings that point to the existence of an endocannabinoid physiological control system (EPCS) that directly impacts human development health and disease. While cannabinoid effects on the brain have received the greatest attention throughout the literature this work looks at research on the endogenous cannabinoid system’s association across all of human physiology including the immune endocrine and reproductive systems. With thoroughly researched and exceptionally insightful contributions from more than three-dozen top-flight researchers representing a cross-section of disciplines from molecular biology genetics and neurology to gynecology physiology and pharmacology this work explores a range of topics as wide as the human body is complex. These topics include the EPCS’s relation to cell development and regulation CNS function immune function modulation reproduction and digestion as well as its function in mental illness neurodegenerative diseases and cancer. The final section in the book considers the significance of endogenous cannabinoids found in some of the simplest multicellular organisms in the animal kingdom as well as in mammalian cells at the earliest stages of development all of which suggests that they play a fundamental role in human biology. | Endocannabinoids The Brain and Body's Marijuana and Beyond

GBP 59.99
1

Cosmology and the Early Universe

Cosmology and the Early Universe

This book discusses cosmology from both an observational and a strong theoretical perspective. The first part focuses on gravitation notably the expansion of the universe and determination of cosmological parameters before moving onto the main emphasis of the book the physics of the early universe and the connections between cosmological models and particle physics. The book provides links with particle physics and with investigations of the theories beyond the Standard Model especially in connection to dark matter and matter-antimatter asymmetry puzzles. Readers will gain a comprehensive account of cosmology and the latest observational results without requiring prior knowledge of relativistic theories making the text ideal for students. Features:Provides a self-contained discussion of modern cosmology results without requiring any prior knowledge of relativistic theories enabling students to learn the first rudiments needed for a rigorous comprehension of cosmological conceptsContains a timely discussion of the latest cosmological results including those from WMAP and the Planck satellite and discuss the cosmological applications of the Nobel Prize 2017 awarded discovery of gravitational waves by the LIGO interferometer and the very high energy neutrinos discovered by the IceCube detectorIncludes original figures complementing mathematical derivations and accounting for the most important cosmological observations in addition to a wide variety of problems with a full set of solutions discussed in detail in an accompanying solutions manual (available upon qualifying course adoption)To view the errata please visit the authors personal href=:http//www. southampton. ac. uk/~pdb1d08>webpage. | Cosmology and the Early Universe

GBP 44.99
1

The Need for Critical Thinking and the Scientific Method

The Vulva and Vaginal Manual

Soundscape and the Built Environment

Soundscape and the Built Environment

Soundscape Basics and Practical Implications Soundscape research represents a paradigm shift as it involves human and social sciences and physical measurements to account for the diversity of soundscapes across countries and cultures. Moreover it treats environmental sounds as a resource rather than a waste. Soundscape and the Built Environment is the first book to systematically discuss soundscape in the built environment. It begins with a presentation of theory and basic background answering questions such as: what is soundscape how is it important and how does it affect people in terms of their health and perception on the acoustic environment. The book then sets out tools for implementing a soundscape approach with measurement techniques mapping and good soundscape practices. It also delivers a series of examples of the application of the soundscape approach in planning design and assessment. Discusses soundscape and environmental noise Explores cultural variations and the way they influence soundscape Introduces binaural measurement technology and psychoacoustics Examines the physical psychological and physiological restorative mechanism of high-quality acoustic environments Presents soundscape mapping based on human perception of sound sources Includes real-world examples and case studies highlighting the key issues in soundscape intervention Soundscape and the Built Environment is written by a group of leading international figures and derives from a four-year EU COST project on Soundscapes of European Cities and Landscapes. It presents a consensus on the current state of the art and is not merely a collection of different views. It is written for acoustic consultants urban planners designers and policy makers as well as for graduate students and researchers.

GBP 69.99
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Unifying the Universe The Physics of Heaven and Earth

The Origin of Snakes Morphology and the Fossil Record

Get Through Radiology for the MRCS and the FRCS

Quarks Leptons and the Big Bang

Secrets of the Moon Understanding and Analysing the Lunar Surface

Secrets of the Moon Understanding and Analysing the Lunar Surface

Secrets of the Moon: Understanding and Analysing the Lunar Surface provides a unique account of the origin of key features on the lunar surface. Containing historical accounts and the latest observations from the field in addition to exciting data from the Apollo manned missions it describes the development of our current understanding of our Moon. It also explores the fracturing of the Moon a topic not explored in other literature in the area and contains a statistical treatment of the smaller craters of the Moon as well as a geological treatment of the larger craters. This moderately technical account is designed to clarify and update the general thinking on the nature and origin of the most important lunar surface features for both undergraduate and research students. It may also be read by the professional scientist especially the astronomer and the geologist who has found little time to study the Moon’s topography in addition to the lunar amateur astronomer and even the dedicated layman with a keen interest in lunar science. The book excludes nearly all mathematical symbols in order to remain accessible to those without a formal education in the area. Key Features: Authored by an expert in the area Presents a comprehensive account of the lunar surface from historical observations to the NASA Apollo manned missions and the latest observations and data in the field Includes a statistical and geological treatment of the craters Dr. Gilbert Fielder is Reader Emeritus at Lancaster University United Kingdom. He performed extended teaching at Lancaster University on Planetary Science and introduced a new degree course on Remote Sensing. Prior to this he was Principal Investigator in NASA’s Heat Capacity Mapping Programme while continuing to head the Lunar and Planetary Unit at Lancaster until retirement. Dr. Fielder has authored several books and presented many BBC and ITA television news programmes as well as popular programmes with Sir Patrick Moore (on the BBC’s The Sky at Night) and on the occasion of the first landing of astronauts on the Moon with David Frost as Chairman in a special programme. | Secrets of the Moon Understanding and Analysing the Lunar Surface

GBP 150.00
1

The Health and Safety Trainer’s Guidebook

Ear Nose and Throat Diseases of the Dog and Cat

Fingerprints Analysis and Understanding the Science

Fingerprints Analysis and Understanding the Science

Fingerprints: Analysis and Understanding the Science Second Edition is a thorough update of Mark Hawthorne’s classic written by two professionals with combined experience not only in crime scene investigations but also as court-recognized experts in latent print examination. Designed as a concise text to cover the fundamental techniques and principles of obtaining and analyzing latent fingerprint evidence the book is laid out and written in an easy to understand format for those front-line professionals collecting and analyzing fingerprint evidence. Over time the degree of sophistication and education on fingerprints and friction ridge analysis has increased. Ultimately through scientific study by pioneers in the field the composition of friction skin soon became evident: that it could be used as a unique identifier of individuals. Now fingerprints and footprints as unique identifiers—and their use in criminal cases—have become commonplace and an essential component of criminal investigation with most cases involving some component of fingerprint evidence. Divided into two parts the book begins with the basics of analysis providing a brief history systematic methods of identification fingerprint pattern types and their associated terminologies and current classifications. The second part of the book discusses the identification and presentation of evidence in the courtroom demonstrating both the traditional manual method of lifting prints and the newer techniques for automated and live scans. Coverage provides instruction on searching and developing latent prints storage and comparison of prints. New to this edition are updated techniques on collecting and preserving fingerprint evidence—including packaging and maintaining chain of custody. More detailed documentation processes and additional chemical and lifting techniques are described including use of light sources latent backing cards and lifting material casting material ten print cards and the enhancement of prints in blood. A discussion of laboratory equipment and comparison tools the addition of photography techniques and recent courtroom challenges to fingerprint evidence is also presented. Fingerprints Second Edition will provide a hands-on fresh look at the most commonly utilized evidence found at crime scenes: fingerprints. The book will provide law enforcement crime scene personnel and students just such an opportunity to easily understand and grasp the concepts and relevant issues associated with friction skin and fingerprint evidence. | Fingerprints Analysis and Understanding the Science

GBP 31.99
1

Firearms the Law and Forensic Ballistics

Firearms the Law and Forensic Ballistics

While gun design has undergone only minimal change over the centuries investigative tools surrounding firearm use have grown significantly in sophistication. Now in its third edition Firearms the Law and Forensic Ballistics has been updated to reflect recently published research and new technology developed since the last volume. Beginning with a discussion of the development of arms and ammunition from the fourteenth century to the present day this book examines:Firearms laws around the world including legal challenges raised in the U. S. by the Daubert decisionFirearms manufacturing processes the mechanisms of various firearms and the linking of a particular bullet or spent cartridge with a suspected weaponThe origins and development of new science in firearms including controversies pioneers and an exposé of the quack purveyors of pseudo-scienceInternal external and terminal (wound) ballisticsThe nature composition and analytical detection of discharge residue left on a suspectThe role of the ballistics expert at all stages of a case ranging from the scene of the shooting incident the post mortem examinations the examination and testing of exhibits at the laboratory and the presentation of evidence in courtRecently introduced computer search techniques applied to captured and digitally stored images of marks left on fired bullets and spent cartridge casesManual microscopic comparison work and computer-based searches on digital images of bullet and cartridge case marks to determine if a particular weapon has been fired in previous casesWritten by an expert with more than 50 years of experience using and handling firearms this text is enhanced with nearly 250 illustrations making it a premier guide to the fundamentals of firearms and related evidentiary considerations.

GBP 69.99
1