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Target Sites of Fungicide Action

Target Sites of Fungicide Action

Target Sites of Fungicide Action presents a critical examination of the mode of action of antifungal inhibitors especially the mechanistical aspects of agricultural fungicides and antifungal drugs. It provides an interdisciplinary approach through its discussions of inhibitors with target sites in sterol biosynthesis molecular studies in fungicide research and fungal resistance. Researchers and students in plant pathology mycology and medicine will find this book to be a comprehensive summary of current knowledge as well as a source of stimulation for future research in the field of applied mycology.

GBP 140.00
1

Chemistry and Molecular Aspects of Drug Design and Action

Chemistry and Molecular Aspects of Drug Design and Action

An ever-increasing demand for better drugs elevated safety standards and economic considerations have all led to a dramatic paradigm shift in the way that drugs are being discovered and developed. Known as rational drug design this contemporary process is defined by three main steps: the discovery of lead compounds surgical manipulation to develop pharmacophores and further optimization to produce the best compounds. Chemistry and Molecular Aspects of Drug Design and Action brings together an impressive collection of world-renowned pharmacochemistry scientists who are currently defining the emergence of rational drug design. Offering insight from their own specialized research these pioneers highlight the variety of approaches being employed in this field including those that start by considering either molecular mechanisms of drug action or the metabolizing enzyme action occurring in the structure of a drug molecule. Another approach they explore is one that starts from the pathobiochemistry and pathophysiology of target diseases. Furthermore the book also considers drug development that makes use of already developed compounds stored in data banks. Divided into five parts each dedicated to various aspects of the classical medicinal chemistry approach the text makes it easy for readers to focus on a field of specific interest. Chemical Biochemical and Biological Aspects of Pathophysiological Conditions Classical Medicinal Chemistry Drug Design Chemical and Molecular Aspects of Drug Action Drug Xenobiotic Metabolism Physical Organic and Theoretical Medicinal Chemistry While each section can be studied independently the combined material in this volume provides the most comprehensive overview available on rational drug design. This work is an invaluable resource both for those entering the field as well as those researchers looking to b

GBP 59.99
1

Strategic Action Planning Now Setting and Meeting Your Goals

Strategic Action Planning Now Setting and Meeting Your Goals

Filling the need for a how-to step-by-step guide to strategic planning Strategic Action Planning NOW! outlines team-based planning in four steps. Gate Gable's techniques provide detailed guidance into planning processes strategic skills recognition of challenges consideration of goals monitoring and measurement and implementation tips to help the reader begin the planning process almost immediately. Written in three parts the author provides exercises with each chapter. Part one covers the pre-planning stages defining who and what your team is and what your teams' goals are. The second part goes over the actual planning identifying the challenges and setting the goals for your team. The third and final part deals with post planning implementation and evaluating your team's progress. | Strategic Action Planning Now Setting and Meeting Your Goals

GBP 175.00
1

Physiological Consequences of Brain Insulin Action

Physiological Consequences of Brain Insulin Action

The brain is crucial for the regulation of whole-body metabolism and behavior. The pancreas-derived hormone insulin modulates brain function and affects energy metabolism as well as cognition. This is partially achieved by modulating several types of brain cell populations including those relevant to satiety and reward. Importantly brains of Alzheimer´s disease patients exhibit a signature of brain insulin resistance with perturbed brain metabolism. This book will cover the basics of insulin signaling in the brain and will describe concepts of insulin resistance a feature of type 2 diabetes. Moreover insulin´s effect on cognitive function will be pointed out and the association between brain insulin resistance and neurodegenerative diseases discussed. Additionally potential behavioral and pharmacological concepts which can affect brain insulin signaling will be summarized. Key Features: Summarizes insulin and the closely related IGF-1 receptor signaling Depicts concepts of insulin resistance Highlights the importance of conserved brain insulin signaling for brain function metabolism and behavior Describes potential behavioral and pharmacological approaches to support brain insulin signaling | Physiological Consequences of Brain Insulin Action

GBP 130.00
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Behavioral Neuroendocrinology

Behavioral Neuroendocrinology

Inspired by Carlos Beyer’s 50 years of pioneering research and influence on his students and colleagues Behavioral Neuroendocrinology builds upon Beyer’s fundamental discoveries and concepts as well as their widespread implications. It presents original research and reviews on mechanisms — genomic and non-genomic — of steroid and protein hormone action; the role of steroid metabolism especially aromatization protein phosphorylation and neurotransmitter action in mediating reproductive behavior and sexual differentiation; and brain and spinal cord mechanisms in sexual behavior and analgesia. This book presents a rich diversity of topics — lactation maternal behavior pheromone action chronobiology allodynia angiogenesis prostate physiology sexual motivation and specific brain systems including vomeronasal system cerebellum preoptic area hypothalamus and spinal cord. This book brings together in one source an international family of researchers whose work has evolved in diverse but related ways from a seminal set of discoveries and concepts in behavioral neuroendocrinology.

GBP 44.99
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Artemisia

Artemisia

A comprehensive overview of this genus Artemisia examines all aspects of the herbs uses and applications its mode of action and clinical importance. Following a comprehensive introduction to the genus the book discusses the botanical phytochemical and biological aspects of a number of important species of Artemisis. Considering that the discovery of artemisinin a highly active antimalarial agent from the Chinese herb A. annua is of considerable importance this volume devotes several chapters to the traditional uses cultivation and phytochemistry of this species and to the development of artemisinin-derived antimalarial agents their mode of action and clinical use.

GBP 59.99
1

Climate Actions Local Applications and Practical Solutions

Climate Actions Local Applications and Practical Solutions

This book offers a diverse set of solid concerted strategies in the development and implementation of specific climate actions in natural and built places where we all live. The book also serves as a conduit of knowledge for those who are unsure on how they can make a difference for their families their communities and the natural places that surround them. Through many actionable examples of mitigation efforts for the ever-present effects of climate change especially for those who may not understand the wide range of climate action opportunities that are available. Scientists academics and community leaders will find concrete examples on how they too can develop and implement climate action solutions. | Climate Actions Local Applications and Practical Solutions

GBP 42.99
1

Biology of Parrotfishes

Biology of Parrotfishes

Parrotfish are found on almost every coral reef in the world. This ubiquity and uniqueness of their feeding action make them one of the most important groups of fishes within coral reef ecosystems. But why exactly are parrotfish so important to reefs? Can the evolution of a particular jaw morphology and feeding action really have had such a large impact on the health and functioning of the world's coral reefs? This book introduces the reader to this fascinating group of fishes (Labridae Scarinae) from the morphological innovation of a jaw that has the power to bite through solid calcium carbonate to the threats currently faced by parrotfish populations around the world. It contains new insights into their diet and food processing ability and lifehistories and concludes with an overview of emerging and future research directions. | Biology of Parrotfishes

GBP 44.99
1

Decision Modes in Complex Task Environments

Decision Modes in Complex Task Environments

Despite intense research on decision-making in action we still know little about when decision-makers rely on deliberate vs. intuitive decision-making in decision situations under complexity and uncertainty. Building on default-interventionist dual-processing theory this book studies decision-making modes (deliberate vs. intuitive) in complex task environments contingent on perceived complexity experience and decision style preference. We find that relatively inexperienced decision-makers respond to increases in subjective complexity with an increase in deliberation and tend to follow their decision style preference. Experienced decision-makers are less guided by their decision preference and respond to increases in subjective complexity only minimally. This book contributes to a developing stream of research linking decision-making with intra-personal and environmental properties and fosters our understanding of the conditions under which decision-makers rely on intuitive vs. deliberate decision modes. In doing so we go one step further towards a comprehensive theory of decision-making in action. | Decision Modes in Complex Task Environments

GBP 69.99
1

Mammalian Endocrinology and Male Reproductive Biology

Mammalian Endocrinology and Male Reproductive Biology

Mammalian Endocrinology and Male Reproductive Biology provides comprehensive and current coverage of the area of endocrinology and male reproductive biology covering not just humans but mammals in general. Written by international experts in their respective fields this multi-author book also covers the latest developments in genomics of androgen action and male infertility. The book begins by covering sexual dimorphism in the central nervous system; structure control of secretion and function of GnRH; and gonadotropins of pituitary origin and their role in gonadal functions. This is followed by an account of hormonal regulation of spermatogenesis and the role of apoptosis in this process. Subsequent chapters center around epididymis regulation of growth and function and sperm motility regulation. The last chapters in the book discuss the structure and function of male accessory sex glands with associated pathologies as well as recent updates in male contraception mechanism of androgen action and genomics of male infertility. Wherever necessary tables and figures have been added for a better understanding. Each chapter is appropriately referenced and contains current information on the latest developments in the field.

GBP 59.99
1

The Chemistry and Metabolism of 4' - Deoxypyridoxine

The Chemistry and Metabolism of 4' - Deoxypyridoxine

This review organizes the existing literature on deoxypyridoxine in order to provide additional insights for developing further work. By providing a thorough analysis of previous work with deoxypyridoxine it can be used more effectively as a tool for examining various metabolic pathways and explored further for its potential clinical use in cancer therapy immunosuppression or other areas. The book also stimulate some new insights into action of vitamin B6 itself. | The Chemistry and Metabolism of 4' - Deoxypyridoxine

GBP 180.00
1

Understanding Radiation Biology From DNA Damage to Cancer and Radiation Risk

Understanding Radiation Biology From DNA Damage to Cancer and Radiation Risk

This book provides a qualitative and quantitative exploration of the action of radiation on living matter which leads to a complete and coherent interpretation of radiation biology. It takes readers from radiation-induced molecular damage in the nucleus of the cell and links this damage to cellular effects such as cell killing chromosome aberrations and mutations before exploring organ damage organism lethality and cancer induction. It also deals with radiological protection concepts and the difficulties of predicting the dose–effect relationship for low-dose and dose rate radiation risk. The book ends with separate chapters dealing with the effects of UV light exposure and risk classification of chemical mutagens both of which are derived by logical extensions of the radiation model. This book will provide the basic foundations of radiation biology for undergraduate and graduate students in medical physics biomedical engineering radiological protection medicine radiology and radiography. Features Presents a comprehensive insight into radiation action on living matter Contains important implications for radiological protection and regulations Provides analytical methods for applications in radiotherapy | Understanding Radiation Biology From DNA Damage to Cancer and Radiation Risk

GBP 94.99
1

Managing Critical Incidents and Large-Scale Event Security

Managing Critical Incidents and Large-Scale Event Security

2017 Award Winner of the ASIS Security Book of the YearNuñez and Vendrell aim to provide the most current and effective resources for managing special events and critical incidents. Their book relies heavily on case studies and after action reports that examine the lessons learned from a multitude of previous events and incidents. In addition the text identifies and examines best practices and recommended approaches providing the reader with a variety of checklists and planning tools. | Managing Critical Incidents and Large-Scale Event Security

GBP 31.99
1

Lubricant Additives Chemistry and Applications Third Edition

Lubricant Additives Chemistry and Applications Third Edition

This indispensable book describes lubricant additives their synthesis chemistry and mode of action. All important areas of application are covered detailing which lubricants are needed for a particular application. Laboratory and field performance data for each application is provided and the design of cost-effective environmentally friendly technologies is fully explored. This edition includes new chapters on chlorohydrocarbons foaming chemistry and physics antifoams for nonaqueous lubricants hydrogenated styrene–diene viscosity modifiers alkylated aromatics and the impact of REACh and GHS on the lubricant industry. | Lubricant Additives Chemistry and Applications Third Edition

GBP 44.99
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Interfaces Between Nanomaterials and Microbes

Interfaces Between Nanomaterials and Microbes

Nanomaterials are becoming ubiquitous; microbes similarly are everywhere. This book focuses on various ways the diverse nanomaterials interact with microbial communities and implications of such interactions. Both toxicity and beneficial effects of nanomaterial-microbe interactions have been covered. This includes areas such as fate and bioavailability of nanomaterials in environments microbial synthesis of nanomaterials and antimicrobial action of nanomaterials. Fairly comprehensive but with narrow focus the book provides useful insights into these interactions which need to be factored in while designing nanoscience based new technologies. | Interfaces Between Nanomaterials and Microbes

GBP 52.99
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Go Green for Environmental Sustainability An Interdisciplinary Exploration of Theory and Applications

Go Green for Environmental Sustainability An Interdisciplinary Exploration of Theory and Applications

This book highlights topics ranging from green chemistry and engineering to bioremediation smart technologies and sustainable business practices. The common threads running through this volume are the need for urgent action a vision for a sustainable future and the awareness that solutions must be widely accessible and advance the welfare of all nations especially in the face of climate change. The authors delineate how we can protect and restore natural ecosystem potential to achieve environmental sustainability. They provide a clear idea of today’s environmental challenges and solutions focus on energy use patterns and the reduction of energy consumption advocate for increased environmental awareness and discuss environmental monitoring systems. The book contains many domestic and international case studies and showcases visionary ideas in action to illustrate sustainability principles. This volume provides an in-depth reference for stakeholders from academia government and industry on the latest research in environmental sustainability solutions. Inspired by the common wisdom that we do not inherit this Earth from our ancestors but instead borrow it from our children the authors offer solutions to emergent problems. This research comprises an important contribution to the global effort to build a more sustainable tomorrow. | Go Green for Environmental Sustainability An Interdisciplinary Exploration of Theory and Applications

GBP 105.00
1

Weed Physiology Volume 2: Herbicide Physiology

Weed Physiology Volume 2: Herbicide Physiology

Volume 2 deals with the mechanisms of herbicide action and of resistance and tolerance to herbicides. The first five chapters of this volume cover the effects of herbicides and adjuvants on the physiology of plants. Professor Black‘s chapter begins by covering the effects of herbicides on photosynthesis including photosynthetic assimilation of nitrogen sulfur and phosphorus. This is followed by Dr. Morelands chapter on herbicide interactions with plant respiration. The third chapter by Professor Bartels deals with the effects of herbicides on chloroplast and cellular development with emphasis on correlating physiological information with ultrasound effects. | Weed Physiology Volume 2: Herbicide Physiology

GBP 170.00
1

Oceanic Acidification A Comprehensive Overview

Oceanic Acidification A Comprehensive Overview

This book critically examines the available literature on oceanic acidification: including a historical review of pH and atmospheric CO2 levels over the millennia; natural and anthropogenic sources of CO2 to the atmosphere and sea surface; chemical physical and biological mode of action; biological effects of acidification to marine plants and animals under laboratory conditions; field observations on seawater chemistry and effects of declining pH; and various technical and political mitigation strategies. Written by Dr. Ronald Eisler a noted authority on chemical risk assessment the book summarizes real and projected effects of oceanic acidification. | Oceanic Acidification A Comprehensive Overview

GBP 69.99
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Resolving Water Conflicts Workbook

Resolving Water Conflicts Workbook

This book works to build trust consensus and capacity to enhance understanding through a water conflict management framework designed to bolster collaborative skills. Built on case-studies analysis and hands-on real-life applications it addresses issues of water insecurity of marginalized systems and communities global water viability institutional resilience and the inclusion of faith-based traditions for climate action. The authors assess the complexities of climate challenges and explain how to create sustainable effective and efficient water approaches for an improved ecological and socioeconomic future within the UN's Sustainable Development Goals. | Resolving Water Conflicts Workbook

GBP 105.00
1

Management of Contaminated Site Problems Second Edition

Management of Contaminated Site Problems Second Edition

This book outlines the strategies used in the investigation characterization management and restoration and remediation for various contaminated sites. It draws on real-world examples from across the globe to illustrate remediation techniques and discusses their applicability. It provides guidance for the successful corrective action assessment and response programs for any type of contaminated land problem and at any location. The systematic protocols presented will aid environmental professionals in managing contaminated land and associated problems more efficiently. This new edition adds twelve new chapters and is fully updated and expanded throughout. | Management of Contaminated Site Problems Second Edition

GBP 150.00
1

Hazardous Laboratory Chemicals Disposal Guide

Hazardous Laboratory Chemicals Disposal Guide

A perennial bestseller Hazardous Laboratory Chemicals Disposal Guide Third Edition includes individual entries for over 300 compounds. The extensive list of references has been updated and includes entries for 15 pesticides commonly used in greenhouses. Emphasis is placed on disposal methods that turn hazardous waste material into non-toxic products. These methods fall into several categories including acid/base neutralization oxidation or reduction and precipitation of toxic ions as insoluble solids. The text also provides data on hazardous reactions of chemicals assisting laboratory managers in developing a plan of action for emergencies such as the spill of any of the chemicals listed.

GBP 180.00
1

Ethnobotany Ethnopharmacology to Bioactive Compounds

Ethnobotany Ethnopharmacology to Bioactive Compounds

Ethnobotany: Ethnopharmacology to Bioactive Compounds comprises of carefully selected studies focusing on the importance of ethnobotanical data as an effective approach towards the discovery of novel ethnopharmacological properties and bioactive compounds that characterize herbal products pharmaceutical drugs and medicinal plants. This book incorporates therapeutic nutritional phytochemistry and pharmacological properties of medicinal plants mechanisms of action and clinical trials of bioactive compounds as well as the molecular basis of the bioactive compounds from the perspective of modern phytochemistry. This book will be useful for a diverse group of readers including students botanists pharmacists chemists herbalists and those researchers interested in ethnobotany and ethnopharmacology. | Ethnobotany Ethnopharmacology to Bioactive Compounds

GBP 140.00
1

100 Diagnostic Dilemmas in Clinical Medicine

100 Diagnostic Dilemmas in Clinical Medicine

100 Diagnostic Dilemmas in Clinical Medicine presents 100 real-life scenarios seen in the hospital and community setting. A succinct summary of the patient's history examination and any initial investigations is followed by a detailed consideration of the diagnosis and management of each case in the short medium and where appropriate long-term. Making speedy and appropriate clinical decisions and choosing the best course of action to take as a result is one of the most important and challenging parts of training to become a doctor. These true-to-life cases will teach students and junior doctors to recognize important medical conditions and to develop their diagnostic and management skills.

GBP 31.99
1

Information Technology and Organizational Learning Managing Behavioral Change in the Digital Age

Information Technology and Organizational Learning Managing Behavioral Change in the Digital Age

Focusing on the critical role IT plays in organizational development the book shows how to employ action learning to improve the competitiveness of an organization. Defining the current IT problem from an operational and strategic perspective it presents a collection of case studies that illustrate key learning issues. It details a dynamic model for effective IT management through adaptive learning techniques—supplying proven educational theories and practices to foster the required changes in your staff. It examines existing organizational learning theories and the historical problems that occurred with companies that have used them as well as those that have failed to use them. | Information Technology and Organizational Learning Managing Behavioral Change in the Digital Age

GBP 74.99
1