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Stem Cells Biology and Application

Stem cell science encompassing basic biology to practical application is both vast and diverse. A full appreciation of it requires an understanding of cell and molecular biology tissue structure and physiology the practicalities of tissue engineering and bioprocessing and the pathways to clinical implementation—including the ethical and regulatory imperatives that our society requires us to address. Expectation and debate have been driven by the allure of regenerative medicine using stem cells as a source of replacements for damaged or aged tissues. The potential of stem cell application goes far beyond this. Highly innovative uses of stem cells are emerging as possible therapies for cancers treating acute damage in conditions such as stroke and myocardial infarction and resolving a whole range of diseases. Stem Cells: Biology and Application presents the basic concepts underlying the fast-moving science of stem cell biology. This textbook is written for an advanced stem cell biology course. The target audience includes senior undergraduates first year graduate students and practitioners in molecular biology biology and biomedical engineering. Stem Cells provides a comprehensive understanding of these unique cells highlighting key areas of research associated controversies case studies technologies and pioneers in the field. | Stem Cells Biology and Application

GBP 66.99

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Transcription Factors

Transcription factors are important in regulating gene expression and their analysis is of paramount interest to molecular biologists studying this area. This book looks at the basic machinery of the cell involved in transcription in eukaryotes and factors that control transcription in eukaryotic cells. It examines the regulatory systems that modulate gene expression in all cells a s well as the more specialized systems that regulate localized gene expression throughout the mammalian organism. Transcription Factors updates classical knowledge with recent advances to provide a full and comprehensive coverage of the field for postgraduates and researchers in molecular biology involved in the study of gene regulation.

GBP 59.99

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Fields Forces and Flows in Biological Systems

Fields Forces and Flows in Biological Systems describes the fundamental driving forces for mass transport electric current and fluid flow as they apply to the biology and biophysics of molecules cells tissues and organs. Basic mathematical and engineering tools are presented in the context of biology and physiology. The chapters are structured in a framework that moves across length scales from molecules to membranes to tissues. Examples throughout the text deal with applications involving specific biological tissues cells and macromolecules. In addition a variety of applications focus on sensors actuators diagnostics and microphysical measurement devices (e. g. bioMEMs/NEMs microfluidic devices) in which transport and electrokinetic interactions are critical. This textbook is written for advanced undergraduate and graduate students in biological and biomedical engineering and will be a valuable resource for interdisciplinary researchers including biophysicists physical chemists materials scientists and chemical electrical and mechanical engineers seeking a common language on the subject.

GBP 59.99

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Protein Actions Principles and Modeling

Protein Actions: Principles and Modeling is aimed at graduates advanced undergraduates and any professional who seeks an introduction to the biological chemical and physical properties of proteins. Broadly accessible to biophysicists and biochemists it will be particularly useful to student and professional structural biologists and molecular biophysicists bioinformaticians and computational biologists biological chemists (particularly drug designers) and molecular bioengineers. The book begins by introducing the basic principles of protein structure and function. Some readers will be familiar with aspects of this but the authors build up a more quantitative approach than their competitors. Emphasizing concepts and theory rather than experimental techniques the book shows how proteins can be analyzed using the disciplines of elementary statistical mechanics energetics and kinetics. These chapters illuminate how proteins attain biologically active states and the properties of those states. The book ends with a synopsis the roles of computational biology and bioinformatics in protein science. | Protein Actions Principles and Modeling

GBP 99.99

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Case Studies in Veterinary Immunology

Case Studies in Veterinary Immunology presents basic immunological concepts in the context of actual cases seen in clinics. It is intended for veterinary medicine students interns residents and veterinarians and serves as a valuable supplement and companion to a variety of core immunology textbooks and courses. The book includes cases describing primary immune system defects secondary immune system defects and hypersensitivity and autoimmune disorders as well as dysproteinemias and lymphoid neoplasia. Drawing on the successful approach of Geha’s Case Studies in Immunology each representative case is preceded by a discussion of the principles underlying that specific immunological mechanism. The case itself includes the presenting complaint (signalment) physical examination findings pertinent diagnostic laboratory data diagnosis and treatment options. In those instances in which a specific disorder occurs in both animals and humans the differences and similarities in the immunological mechanisms and manifestations of the disease are explored. End of case questions highlight important concepts and serve as a review aid for students. Details on standard vaccines and vaccination schedules as well as descriptions of the types of assays used for evaluation of the immune system are included as appendices.

GBP 42.99

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Biology of Aging

Biology of Aging Second Edition presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging longevity and age-related disease. Intended for undergraduate biology students it describes how the rate of biological aging is measured; explores the mechanisms underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. The book also includes end-of-chapter discussion questions to help students assess their knowledge of the material. Roger McDonald received his Ph. D. from the University of Southern California and is Professor Emeritus in the Department of Nutrition at the University of California Davis. Dr. McDonald’s research focused on mechanisms of cellular aging and the interaction between nutrition and aging. His research addressed two key topics in the field: the relationship between dietary restriction and lifespan and the effect of aging on circadian rhythms and hypothalamic regulation. You can contact Dr. McDonald at rbmcdonald@ucdavis. edu. Related Titles Ahmad S. I. ed. Aging: Exploring a Complex Phenomenon (ISBN 978-1-1381-9697-1) Moody H. R. & J. Sasser. Gerontology: The Basics (ISBN 978-1-1387-7582-4) Timiras P. S. Physiological Basis of Aging and Geriatrics (ISBN 978-0-8493-7305-3)

GBP 56.99

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Cell Boundaries How Membranes and Their Proteins Work

The central themes of Cell Boundaries concern the structural and organizational principles underlying cell membranes and how these principles enable function. By building a biological and biophysical foundation for understanding the organization of lipids in bilayers and the folding assembly stability and function of membrane proteins the book aims to broaden the knowledge of bioscience students to include the basic physics and physical chemistry that inform us about membranes. In doing so it is hoped that physics students will find familiar territory that will lead them to an interest in biology. Our progress toward understanding membranes and membrane proteins depends strongly upon the concerted use of both biology and physics. It is important for students to know not only what we know but how we have come to know it so Cell Boundaries endeavours to bring out the history behind the central discoveries especially in the early chapters where the foundation is laid for later chapters. Science is far more interesting if as students we can appreciate and share in the adventures—and misadventures—of discovering new scientific knowledge. Cell Boundaries was written with advanced undergraduates and beginning graduate students in the biological and physical sciences in mind though this textbook will likely have appeal to researchers and other academics as well. Highlights the history of important central discoveries Early chapters lay the foundation for later chapters to build on so knowledge is amassed High-quality line diagrams illustrate key concepts and illuminate molecular mechanisms Box features and spreads expand on topics in main text including histories of discoveries special techniques and applications | Cell Boundaries How Membranes and Their Proteins Work

GBP 82.99

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Biology for the Health Sciences Mechanisms of Disease

Biology is central to our understanding of health and disease and to the development of effective treatments and thus it is critical that health professionals have a solid grounding and knowledge comfort in the pathogenesis and mechanisms of disease processes. This innovative new textbook draws these topics together providing an accessible introduction across four central disciplines - basic biology biotechnology non-infectious disease and infectious disease. Key Features: Provides students of biology and those going into health care professions with a strong foundation to understand the pathogenesis of disease at the molecular and cellular level Focuses on the etiology and pathophysiology of the major human diseases by body system including diabetes and nutritional disorders cardiovascular disease neurodegenerative diseases and cancer aligned to medicine and health science course structure Covers mechanisms of infectious disease transmission as well as disease pathophysiology and considers the impact of antibiotic resistance Reviews the applications of biotechnology and genomics to human health in diagnosis and treatment as well as to our understanding of disease and disease surveillance Each chapter contains a mini glossary of key terms and associated definitions and review questions allow students to assess how much of the chapter they have understood Digital resources accompany the textbook such as interactive quizzes for students to engage with and figure slides of the book's illustrations that instructors can use in lectures Enhanced throughout with plentiful illustrations Biology for the Health Sciences is an essential companion for any student of the health sciences and for biological science students studying the causes of disease as part of a wider course. | Biology for the Health Sciences Mechanisms of Disease

GBP 49.99

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Strelkauskas' Microbiology A Clinical Approach

As with the much-praised prior editions the third edition of Strelkauskas' Microbiology: A Clinical Approach remains a comprehensive introductory textbook written specifically for pre-nursing nursing and allied health students. Clinically relevant throughout it uses the theme of infection as its foundation fitting closely with the 'One Health' approach that is considered increasingly central to the effective control of zoonoses and to combatting antimicrobial resistance. The third edition has been thoroughly revised and updated to reflect the latest developments including the emergence of the SARS-CoV-2 virus and associated COVID-19 pandemic. The book is accompanied by a robust instructor ancillary package that allows educators to incorporate readily the book’s unique approach into their lectures and includes additional materials for students to supplement classroom learning and encourage and support study and self-reflection. Key Features: Student-focused with all elements carefully designed to help students engage with and understand difficult concepts and to spark and hold interest Dedicated learning skill section introduces practical strategies for improving comprehension and retention Numerous text features further support learning and teaching including chapter overviews fast facts case studies and human stories and ‘why is this important?’ highlights A variety of question-and-answer types for self-testing and reflection to support and assess basic learning to challenge students to integrate important concepts and ask students to apply what they have just learned to a specific clinical setting or problem All supported by a comprehensive suite of online resources including lecturer support material and for students interactive questions lecture notes MicroMovies and the BugParade The book is an excellent resource to guide and support inter-professional education in the health sciences and an ideal entry-point to the subject for anyone coming from another discipline and invaluable supplementary reading for medical microbiology and biomedical science students. | Strelkauskas' Microbiology A Clinical Approach

GBP 54.99

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