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Introduction to Limb Arthrology

Introduction to Limb Arthrology

This book discusses arthrology in general and of the upper and lower limbs specifically. It covers the examination of each joint of both limbs considering their basic anatomy and physiology. It presents the various tests required for examining the joints and articulations and the systematic approaches that should be followed in cases of diagnosis of diseases and injuries related to them as well as in specific cases of disease and injuries. The book also defines special tests required in varied situations and mentions precautions that should be taken while examining patients of specific ages or work groups. To simplify the explanation and promote education original photographs either documented during clinical examination of the foot and ankle or taken using models are used in this book. These photographs are from accomplished orthopedic surgeons and have not been documented anywhere before. In addition some chapters showcase line diagrams sketched to illustratively discuss the information being presented. The book will help readers understand the importance of this expanding sub-specialty in orthopedics and will be useful for orthopedic surgeons taking exams in different universities of the world as well as sub-speciality exams of each joint. | Introduction to Limb Arthrology

GBP 216.00
1

Nanomedicine in Cancer

Nanomedicine in Cancer

This book is the first in a series compiling highly cited articles in nanomedicine recently. The series is edited by Lajos P. Balogh a prominent nanotechnology researcher and journal editor. The first book content is about nanotechnology in cancer research. It also includes a wide variety of must-know topics that will appeal to any researcher involved in nanomedicine macromolecular science cancer therapy and drug delivery research. These 31 articles collected here have already acquired more than 3500 citations (i. e. over a hundred on average) highlighting the importance and recognized professional interest of the scientists working in this field. | Nanomedicine in Cancer

GBP 347.00
1

The Hip Joint Modified Posterior Approach

The Hip Joint Modified Posterior Approach

This book summarizes the lifetime work of Dr K. Mohan Iyer and is based on his research done at the University of Liverpool UK where he devised a modified posterior approach to the hip joint and has been following it from 1981 till today. The book discusses the anterior approach to the hip on a standard operating table using a leg holder with a combined spinal anesthetic and general anesthetic. It studies total hip replacement as a day-case as an evolution in total hip replacement and presents the principles of anterior approach for total hip arthroplasty including discussions on the choice of patients superficial and deep dissection and dedicated surgical instruments. It provides extensive details on the direct anterior approach (DAA) and shows how the DAA to the hip can be carried out on a plain table which can be useful in countries in Asia such as India without the use of special operating tables and dedicated surgical instruments for the same. The book is helpful for the upcoming postgraduates in orthopedics anywhere in the world to be well versed in DAA to the hip joint. | The Hip Joint Modified Posterior Approach

GBP 193.00
1

Lipid-Based Drug Delivery Systems Principles and Applications

Lipid-Based Drug Delivery Systems Principles and Applications

This book appraises the role of lipid-based drug delivery systems (LBDDSs) with respect to the bioavailability and controlled delivery of complex drug molecules for improving their clinical viability. It covers the latest developments and advancements in the field of drug delivery and explores and compiles information on the current situation of lipid-based formulations used as versatile excipients and all their possible routes to improve therapeutic benefits. The book discusses novel formulations such as depot formulations micro- and nanoemulsions solid lipid nanoparticles (SLNs) nanostructured lipid carriers (NLCs) liposomes nanoliposomes micelles nanosuspensions lipid implants and inserts and lipid nanotubes. It presents preparation methods of LBDDSs and their physicochemical properties and portrays their various application angles and their impacts on drug-conveyance frameworks when employed in vitro and in vivo. The book is beneficial for researchers working on lipid-based drug formulations as well as biological and translational drug delivery. It is also a useful resource for course work of students of various academic degree programs such as pharmacy health sciences biotechnology and microbiology; postgraduate and PhD students; and postdoctoral fellows researching on nanomedicine-based drug delivery systems. | Lipid-Based Drug Delivery Systems Principles and Applications

GBP 270.00
1

Handbook of Materials for Nanomedicine Lipid-Based and Inorganic Nanomaterials

Handbook of Materials for Nanomedicine Lipid-Based and Inorganic Nanomaterials

In the fast-developing field of nanomedicine a broad variety of materials have been used for the development of advanced delivery systems for drugs genes and diagnostic agents. With the recent breakthroughs in the field we are witnessing a new age of disease management which is governed by precise regulation of dosage and delivery. This book presents the advances in the use of lipid-based and inorganic nanomaterials for medical imaging diagnosis theranostics and drug delivery. The materials discussed include liposome-scaffold systems elastic liposomes targeted liposomes solid lipid nanoparticles lipoproteins exosomes porous inorganic nanomaterials silica nanoparticles and inorganic nanohybrids. The book provides all available information about them and describes in detail their advantages and disadvantages and the areas where they could be utilized successfully. | Handbook of Materials for Nanomedicine Lipid-Based and Inorganic Nanomaterials

GBP 193.00
1

Diradicaloids

Diradicaloids

π-Conjugated molecules with an even number of π-electrons usually have a closed-shell ground state. However recent studies have demonstrated that a certain type of molecules could show open-shell singlet ground state and display diradical-like (diradicaloid) behavior. Their electronic structure can be understood in terms of the “diradical character” and “aromaticity” concepts. They display very different electronic properties from traditional closed-shell π-conjugated molecules and could be used as next-generation molecular materials. This book provides a comprehensive review on the chemistry physics and material applications of open-shell singlet diradicaloids. Particularly it elaborates the fundamental structure–diradical character–electronic property relationships both theoretically and experimentally. The book has been written by leading scientists in the field from Japan Germany Spain Italy China and Singapore.

GBP 193.00
1

Medical Regulatory Affairs An International Handbook for Medical Devices and Healthcare Products

Medical Regulatory Affairs An International Handbook for Medical Devices and Healthcare Products

This handbook covers medical device regulatory systems in different countries ISO standards for medical devices clinical trial and regulatory requirements and documentation for application. It is the first to cover the medical device regulatory affairs in Asia. Experts from influential international regulatory bodies including the US Food and Drug Administration (FDA) UK Medicines and Healthcare Products Regulatory Agency Japan Pharmaceuticals and Medical Devices Agency Saudi Food and Drug Authority Korea Testing Laboratory Taiwan FDA World Health Organization Asian Harmonization Working Party Regulatory Affairs Professionals Society and British Standards Institution have contributed to the book. Government bodies the medical device industry academics students and general readers will find the book immensely useful for understanding the global regulatory environment and in their research and development projects. | Medical Regulatory Affairs An International Handbook for Medical Devices and Healthcare Products

GBP 193.00
1

Handbook of Low-Level Laser Therapy

Handbook of Low-Level Laser Therapy

Low-Level Laser Therapy (LLLT) also known as photobiomodulation is almost 50 years old and recently has been getting increasing acceptance from the scientific medical and veterinary communities. Discoveries are constantly being made about the cellular and molecular mechanisms of action the range of diseases that can be treated is also rising and home use LED devices are becoming common. This book compiles cutting-edge contributions from the world’s leading experts in Photobiomodulation and LLLT. Chapters cover general concepts mechanisms of action in vitro studies pre-clinical animal studies veterinary applications and a wide range of clinical topics. Edited by Michael Hamblin from Massachusetts General Hospital and Harvard Medical School aided by two prominent researchers (Marcelo Sousa and Tanupriya Agrawal) this book will appeal to anyone involved in the basic science translational aspects and clinical applications of LLLT. | Handbook of Low-Level Laser Therapy

GBP 335.00
1

MXenes From Discovery to Applications of Two-Dimensional Metal Carbides and Nitrides

MXenes From Discovery to Applications of Two-Dimensional Metal Carbides and Nitrides

Since their discovery in 2011 MXenes (2D carbides nitrides and carbonitrides of early transition metals) have developed into one of the largest and most intensively studied families of 2D materials. They offer unique properties and are being explored in a large variety of applications. This book compiles the most important research from a pioneer of the field Professor Yury Gogotsi and his interdisciplinary research team as well as numerous collaborators worldwide. It reports on the discovery and rise of MXenes and describes their synthesis and processing properties and incorporation into polymer ceramic and metal matrices to produce composites. It also discusses the potential of MXenes for use in energy storage optics electronics and sensing as well as biomedical environmental and electrocatalysis applications. The book will appeal to anyone interested in nanomaterials and their synthesis properties and applications. | MXenes From Discovery to Applications of Two-Dimensional Metal Carbides and Nitrides

GBP 385.00
1

Characterization of Nanocomposites Technology and Industrial Applications

Characterization of Nanocomposites Technology and Industrial Applications

These days advanced multiscale hybrid materials are being produced in the industry studied by universities and used in several applications. Unlike for macromaterials it is difficult to obtain the physical mechanical electrical and thermal properties of nanomaterials because of the scale. Designers however must have knowledge of these properties to perform any finite element analysis or durability and damage tolerance analysis. This is the book that brings this knowledge within easy reach. What makes the book unique is the fact that its approach that combines multiscale multiphysics and statistical analysis with multiscale progressive failure analysis. The combination gives a very powerful tool for minimizing tests improving accuracy and understanding the effect of the statistical nature of materials in addition to the mechanics of advanced multiscale materials all the way to failure. The book focuses on obtaining valid mechanical properties of nanocomposite materials by accurate prediction and observed physical tests as well as by evaluation of test anomalies of advanced multiscale nanocomposites containing nanoparticles of different shapes such as chopped fiber spherical and platelet in polymeric ceramic and metallic materials. The prediction capability covers delamination fracture toughness impact resistance conductivity and fire resistance of nanocomposites. The methodology employs a high-fidelity procedure backed with comparison of predictions with test data for various types of static fatigue dynamic and crack growth problems. Using the proposed approach a good correlation between the simulation and experimental data is established. | Characterization of Nanocomposites Technology and Industrial Applications

GBP 193.00
1

Pharmaceutical Biocatalysis Fundamentals Enzyme Inhibitors and Enzymes in Health and Diseases

Pharmaceutical Biocatalysis Fundamentals Enzyme Inhibitors and Enzymes in Health and Diseases

This book provides an overview of the world market of therapeutic enzymes and enzyme inhibitors rare diseases orphan drugs the costs of drug development and therapies and enzymes in downstream processing of pharmaceuticals. It discusses carbonic anhydrase inhibitors and their multiple drug interactions carboxylesterase inhibitors for pharmaceutical applications employment of inhibitors for the treatment of neurodegenerative diseases use of engineered proteins bioactive peptides and fibrinolytic enzymes for thrombolytic therapy and enzymes important for the design and development of new drugs/drug metabolites such as aldehyde oxidases and cytochrome P450 enzymes and the role the latter play in vascular biology and pathophysiology. The treatment of cancer is explored in connection with enzymatic amino acid deprivation therapies and new drugs that act as chemical degraders of oncogenic proteins. The book also introduces the resistance mechanisms of cancer. Furthermore it provides an insight into the relationship between pathological conditions of cardiovascular disease and oxidative stress. The text also focuses on the potential use of nanoparticles as carriers for enzymes with medical relevance computer-aided drug design for the identification of multi-target directed ligands and the development of improved therapeutics through a glycan-“designer” approach. It concludes with an introduction to the chemoenzymatic synthesis of drugs. | Pharmaceutical Biocatalysis Fundamentals Enzyme Inhibitors and Enzymes in Health and Diseases

GBP 193.00
1

Nano-Enabled Medical Applications

Nano-Enabled Medical Applications

This book is the second in a series presenting articles that received the most citations in recent years in nanomedicine. The series is edited by a prominent nanotechnology researcher and editor-in-chief of Precision Nanomedicine. The theme of the second volume is about nano-enabled medical applications. The 19 articles collected here have already acquired more than 12 500 citations highlighting the importance and professional recognition of the work of these scientists in nanomedicine. The content includes the general overview of the field and a wide variety of applications that have been impossible without nanoscience and nanotechnology.

GBP 193.00
1

Heterostructured Materials Novel Materials with Unprecedented Mechanical Properties

Heterostructured Materials Novel Materials with Unprecedented Mechanical Properties

Heterostructured (HS) materials represent an emerging class of materials that are expected to become a major research field for the communities of materials mechanics and physics in the next couple of decades. One of the biggest advantages of HS materials is that they can be produced by large-scale industrial facilities and technologies and therefore can be commercialized without the scaling up and high-cost barriers that are often encountered by other advanced materials. This book collects recent papers on the progress in the field of HS materials especially their fundamental physics. The papers are arranged in a sequence of chapters that will help new researchers entering the field to have a quick and comprehensive understanding of HS materials including the fundamentals and recent progress in their processing characterization and properties. | Heterostructured Materials Novel Materials with Unprecedented Mechanical Properties

GBP 193.00
1

Electrophosphorescent Materials and Devices

Electrophosphorescent Materials and Devices

Organic LEDs (OLEDs) in mobile displays have been in large-scale production for over a decade and OLED-based televisions are rapidly gaining traction in the marketplace. OLEDs are on the verge of entering the solid-state lighting market in a big way. The OLED technology gives higher color purity and is more efficient than any of the competing technologies. When produced at scale OLEDs are also economical. A key limitation in the development of OLEDs was the efficient conversion of all of the electrical energy put into the device into light. Until the late 1990s the maximum efficiency of OLEDs was limited to 25% (photons/electrons) but this limitation was removed and OLEDs with 100% efficiency were reported in the early 2000s. This advance in OLED technology was driven by the author of this book. He and his collaborators developed electrophosphorescence which is essential in reaching the 100% efficiency that is now commonplace in commercial devices. | Electrophosphorescent Materials and Devices

GBP 193.00
1

Drug Delivery with Targeted Nanoparticles In Vitro and In Vivo Evaluation Methods

Drug Delivery with Targeted Nanoparticles In Vitro and In Vivo Evaluation Methods

Nanotechnology has the potential to change every part of our lives. Today nanotechnology-based products are used in many areas and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However compared with conventional drug delivery systems few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition obtaining targeted nanoparticle systems is quite complex and requires several evaluation mechanisms. This book discusses the production characterization regulation and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles’ (i) in vitro characterization such as particle size stability ligand density and type; (ii) in vivo behavior for different targeting areas such as tumor brain and vagina; and (iii) current advances in this field including clinical trials and regulation processes. | Drug Delivery with Targeted Nanoparticles In Vitro and In Vivo Evaluation Methods

GBP 385.00
1