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Algorithms for Next-Generation Sequencing

Next-Generation Solar Cells Principles and Materials

Next Generation Safety Leadership From Compliance to Care

Preventing Misguided Reading Next Generation Guided Reading Strategies

Next-Generation Sequencing Data Analysis

Next-Generation Sequencing Data Analysis

Next-generation DNA and RNA sequencing has revolutionized biology and medicine. With sequencing costs continuously dropping and our ability to generate large datasets rising data analysis becomes more important than ever. Next-Generation Sequencing Data Analysis walks readers through next-generation sequencing (NGS) data analysis step by step for a wide range of NGS applications. For each NGS application this book covers topics from experimental design sample processing sequencing strategy formulation to sequencing read quality control data preprocessing read mapping or assembly and more advanced stages that are specific to each application. Major applications include: RNA-seq: Both bulk and single cell (separate chapters) Genotyping and variant discovery through whole genome/exome sequencing Clinical sequencing and detection of actionable variants De novo genome assembly ChIP-seq to map protein-DNA interactions Epigenomics through DNA methylation sequencing Metagenome sequencing for microbiome analysis Before detailing the analytic steps for each of these applications the book presents introductory cellular and molecular biology as a refresher mostly for data scientists the ins and outs of widely used NGS platforms and an overview of computing needs for NGS data management and analysis. The book concludes with a chapter on the changing landscape of NGS technologies and data analytics. The second edition of this book builds on the well-received first edition by providing updates to each chapter. Two brand new chapters have been added to meet rising data analysis demands on single-cell RNA-seq and clinical sequencing. The increasing use of long-read sequencing has also been reflected in all NGS applications. This book discusses concepts and principles that underlie each analytic step along with software tools for implementation. It highlights key features of the tools while omitting tedious details to provide an easy-to-follow guide for practitioners in life sciences bioinformatics biostatistics and data science. Tools introduced in this book are open source and freely available.

GBP 74.99
1

Mexico's Political Stability The Next Five Years

Water Poverty The Next “Oil” Crisis

Natural Capitalism The Next Industrial Revolution

Next Steps Decision Cases for Social Work Practice

Business Strategies for the Next-Generation Network

Business Strategies for the Next-Generation Network

Carriers and service providers have united around the concept of the Next-Generation Network (NGN). Although leveraging a broad basket of Internet technologies the NGN is not being planned as the next-generation Internet. In its intention and architecture it is more accurately described as Broadband-ISDN release 2. 0. The NGN transition is hard for both practitioners and observers to understand because it weaves together a number of distinct strands: the development of a new architecture and technology base including advanced IT automation systems the development of a portfolio of ‘new wave’ products and services which exploits the power of the new network the design of a new kind of organization which can utilize the higher levels of automation in the NGN and reduce costs and the development of an effective transition plan which can smoothly move operators from their current legacy networks systems and processes to the NGN future. The book begins with a review of the failures of previous attempts by carriers to retool for the future. It describes in detail the technologies and capabilities supporting “new wave’” services focusing particularly on multimedia interactive services TV and Video-on-Demand. The author looks at the IMS layer and how it interworks both downwards into the QoS-enabled IP transport layer and upwards to enable new kinds of applications. However equal attention is addressed to the business models of players in the value chain carriers service providers broadcasters and production companies. The author then examines how carriers have attempted to remodel themselves as IP companies along the dimensions of people processes and IT automation systems describing the lessons to be learned from numerous failures. He identifies more innovativebusiness models exploresPeer-to-Peer networking and reviews the prospects for | Business Strategies for the Next-Generation Network

GBP 54.99
1

Colloquial Irish 2 The Next Step in Language Learning

Bioinformatics A Practical Guide to Next Generation Sequencing Data Analysis

Construction Superintendents Essential Skills for the Next Generation

GBP 62.99
1

Future Office Next-generation workplace design

Next Generation Wireless Terahertz Communication Networks

Nano-Interconnect Materials and Models for Next Generation Integrated Circuit Design

The Next Generation of Solution Focused Practice Stretching the World for New Opportunities and Progress

Dear Development Practitioner Advice for the Next Generation

Next Steps with Academic Conversations New Ideas for Improving Learning Through Classroom Talk

Next Steps with Academic Conversations New Ideas for Improving Learning Through Classroom Talk

Dr. Jeff Zwiers an educational researcher at Stanford University has spent the last 15 years analyzing classroom conversations to see how they can be better used and improved in classroom settings. Teachers who have worked with him report significant growth in students’ engagement content learning language creativity and sense of agency. Zweirs introduced his initial vision for classroom conversations Academic Conversations: Classroom Talk that Fosters Critical Thinking and Content Understanding. His follow-up book Next Steps with Academic Conversations: New Ideas for Improving Learning Through Classroom Talk expands the first book with updated classroom strategies and practices. In this new version teachers will discover: How to introduce buildable ideas and teach students how to develop and support them Equitable classroom discussions and how diverse backgrounds conversing can benefit social skills and emotional intelligence Highlights of new research-based theories on classroom conversation Ways to develop students' confidence in conversation and how classroom skills can apply to real world interactions This resource is the product of his extensive research co-teaching and collaborating with a wide range of educators. It was written for busy teachers who want a practical guide for strengthening the quality and quantity of productive conversations in their lessons. | Next Steps with Academic Conversations New Ideas for Improving Learning Through Classroom Talk

GBP 29.99
1

A Vision for the U.S. Forest Service Goals for Its Next Century

Colloquial Russian 2 The Next Step in Language Learning