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Apollo Discovery Sounder Beacon Base with Isolator 45681-393APO

Apollo Discovery Sounder Beacon Base with Isolator 45681-393APO

Apollo Discovery Sounder Beacon Base with Isolator 45681-393APOThe Discovery SounderVisual Indicator Base makes full use ofthe Discovery protocol. For ease of commissioning a Magnetic Wand can be used to test and adjust each sounder locally.Key Features It is possible to set individual control of the sounder and visual indicatorVolume and tone settings can be selected from the control panelTones can be used for other purposes in addition to warning of fire ideal for schoolsEnables soft start option ideal for hospitals and nursing homesElectronic bell tone

GBP 59.87
1

Service-Oriented Distributed Knowledge Discovery

Service-Oriented Distributed Knowledge Discovery

A new approach to distributed large-scale data mining service-oriented knowledge discovery extracts useful knowledge from today’s often unmanageable volumes of data by exploiting data mining and machine learning distributed models and techniques in service-oriented infrastructures. Service-Oriented Distributed Knowledge Discovery presents techniques algorithms and systems based on the service-oriented paradigm. Through detailed descriptions of real software systems it shows how the techniques models and architectures can be implemented. The book covers key areas in data mining and service-oriented computing. It presents the concepts and principles of distributed knowledge discovery and service-oriented data mining. The authors illustrate how to design services for data analytics describe real systems for implementing distributed knowledge discovery applications and explore mobile data mining models. They also discuss the future role of service-oriented knowledge discovery in ubiquitous discovery processes and large-scale data analytics. Highlighting the latest achievements in the field the book gives many examples of the state of the art in service-oriented knowledge discovery. Both novices and more seasoned researchers will learn useful concepts related to distributed data mining and service-oriented data analysis. Developers will also gain insight on how to successfully use service-oriented knowledge discovery in databases (KDD) frameworks.

GBP 59.99
1

Apollo Discovery Red Open-Area Sounder Beacon - 58000-005APO

Apollo Discovery Red Open-Area Sounder Beacon - 58000-005APO

Apollo Discovery Red Open-Area Sounder Beacon - 58000-005APOThe Discovery Open-Area Sounder Visual Indicator makes full use of the Discovery protocol andhas beendesigned for use in indoor and open areas. Whenthe fire system is being commissioned a Magnetic Wand can be used to adjust and test each sounder locally.Key Features 15 tone pairsIt is possible to set individual control of the sounder and visual indicatorVolume and tone settings can be selected from the control panelTones can be used forother purposes in addition to warning of fire making the device ideal for use in schools etc.Soft start option ideal for hospitals and nursing homesGroup and global control for increased response time

GBP 73.38
1

Apollo Discovery Cat O. Discovery Sounder VAD Base with Isolator 45681-700APO

Apollo Discovery Cat O. Discovery Sounder VAD Base with Isolator 45681-700APO

Apollo Discovery Cat O. Discovery Sounder VAD Base with Isolator 45681-700APOThe Discovery Sounder VAD Base makes full use of the Discovery protocol. For ease of commissioning a Magnetic Wand can be used to test and adjust each sounder VAD locally.Key FeaturesEN54-23 certifiedFlash rate of 0.5HzIt is possible to set individual volume of the sounder from the panel15 pairs of tones including IMO code 1A General Emergency Alarm and IMO Code 2 All ClearBuilt in isolatorBrand InformationDiscovery is a range of high-specification analogue addressable fire detectors and alarm devices. Discovery detectors offer effective false alarm management by a combination of EN 54 approved operating modes and sophisticated algorithms. Drift compensation further reduces the likelihood of false alarms caused by a build-up of dust in the sensing chamber. In addition to the familiar smoke and heat detectors the Discovery range features two multisensor detectors. One is an opticalheat multisensor which can be used to protect against many types of fire risk. The other is a carbon monoxideheat multisensor which protects against both smouldering fires and those generating heat.OperationThe Discovery Multisensor construction is similar to that of the optical detector but uses a different lid and optical mouldings to accommodate the thermistor heat sensor. The Discovery OpticalHeat Multisensor Detector contains an optical smoke sensor and a thermistor temperature sensor whose outputs are combined to give the final analogue value. The way in which the signals from the two sensors are combined depends on the response mode selected.The five modes provide response behaviour which incorporates pure heat detection pure smoke detection and a combination of both. The multisensor is therefore useful over the widest range of applications. The signals from the optical smoke sensing element and the temperature sensor are independent and represent the smoke level and the air temperature respectively in the vicinity of the detector.The detectors micro-controller processes the two signals according to the mode selected. When the detector is operating as a multisensor the temperature signal processing extracts only rate-of-rise information for combination with the optical signal. In these modes the detector will not respond to a slow temperature increase even if the temperature reaches a high level. A large sudden change in temperature can however cause an alarm without the presence of smoke if sustained for 20 seconds.

GBP 78.12
1

Laser Tools Oil Filter Wrench Set 3 Piece - for JLR

Laser Tools Oil Filter Wrench Set 3 Piece - for JLR

This 3-set oil filter wrench with 74mm x 14 flute is designed for a variety of Jaguar and Land Rover vehicles. Features and Benefits This 3 Piece set allows for easier removal of filters for a variety of Jaguar and Land Rover vehicles Typical applications Jaguar vehicles including: XKR (2007), XJ6(2008), XK(2008), Daimler (2008), Sovereign (2008 - 2009), X-Type (2008 - 2010), XF (2010 - 2013), XJ (2010 - 2013) Range Rover vehicles including Range Rover Sport, Velar, Evoque, Discovery Sport (from 2008); Discovery 2 (1998 - 03); Discovery 3 (2004 - 2008); Discovery 4 (2009 - 2015); Discovery 5 (from 2016)

GBP 75.99
2

Textbook of Drug Design and Discovery

Textbook of Drug Design and Discovery

Building on the success of the previous editions the Textbook of Drug Design and Discovery Fifth Edition has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry pharmacy pharmacology biochemistry and medicine. The information is presented in an up-to-date review form with an underlying and fundamental focus on the educational aspects. Beginning with an introduction to drug design and discovery the first eight chapters cover molecular recognition ligand-based drug design and biostructure-based drug design. The authors also discuss drug-like properties and decision making in medicinal chemistry chemical biology natural products in drug discovery and in vivo imaging in drug discovery. The middle six chapters provide an overview of peptide and protein drug design prodrugs in drug design and development and enzyme inhibitors. The authors also go through receptors (structure function and pharmacology) ion channels (structure and function) and neurotransmitter transporters (structure function and drug binding). The following chapters address important neurotransmitter systems GABA and glutamic acid receptors and transporter ligands acetylcholine histamine dopamine and serotonin and opioid and cannabinoid receptors. The book concludes with an examination of neglected diseases anticancer agents tyrosine kinase receptors and antibiotics.

GBP 48.99
1

Drug Discovery and Development Third Edition

Drug Discovery and Development Third Edition

Drug Discovery and Development Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies biotechnology approaches and evaluation of efficacy and safety of drug candidates through preclinical testing. This book also greatly expands the focus on the clinical pharmacology regulatory and business aspects of bringing new drugs to the market and offers coverage of essential topics for companies involved in drug development. Historical perspectives and predicted trends are also provided. Features:Highlights emerging scientific fields relevant to drug discovery such as the microbiome nanotechnology and cancer immunotherapy; and novel research tools such as CRISPR and DNA-encoded librariesCase study detailing the discovery of the anti-cancer drug lorlatinibVenture capitalist commentary on trends and best practices in drug discovery and developmentComprehensive review of regulations and their impact on drug development highlighting special populations orphan drugs and pharmaceutical compoundingMultidiscipline functioning of an Academic Research Enterprise plus a chapter on Ethical Concerns in ResearchContributions by 70+ experts from industry and academia specialists who developed and are practitioners of the science and business

GBP 44.99
1