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Developments in Lymphoid Cell Biology

Developments in Lymphoid Cell Biology

In this volume the author by no means attempted to give a comprehensive view of the myriad of recent developments in immunology. The author has attempted after introducing sufficient background in chapter 1 to highlight certain areas of lymphoid cell biology which are given less attention in current thinking but which seem to the author to offer exciting prospects for research. In other cases the important topics of transplantation and tolerance are looked at from points of view which are somewhat less conventional in the hope that these aspects may stimulate others to look at the yet unsolved problems in these areas. In making the selection of topics and indeed in the selection of references within each chapter the contributors and the author have attempted to select those which offered what seemed to be the best sources of information. They do not wish to minimize the important contributions of others but are guided by constraints of brevity and cogent expression. | Developments in Lymphoid Cell Biology

GBP 140.00
1

Stem Cells Biology and Application

Stem Cells Biology and Application

Stem cell science encompassing basic biology to practical application is both vast and diverse. A full appreciation of it requires an understanding of cell and molecular biology tissue structure and physiology the practicalities of tissue engineering and bioprocessing and the pathways to clinical implementation—including the ethical and regulatory imperatives that our society requires us to address. Expectation and debate have been driven by the allure of regenerative medicine using stem cells as a source of replacements for damaged or aged tissues. The potential of stem cell application goes far beyond this. Highly innovative uses of stem cells are emerging as possible therapies for cancers treating acute damage in conditions such as stroke and myocardial infarction and resolving a whole range of diseases. Stem Cells: Biology and Application presents the basic concepts underlying the fast-moving science of stem cell biology. This textbook is written for an advanced stem cell biology course. The target audience includes senior undergraduates first year graduate students and practitioners in molecular biology biology and biomedical engineering. Stem Cells provides a comprehensive understanding of these unique cells highlighting key areas of research associated controversies case studies technologies and pioneers in the field. | Stem Cells Biology and Application

GBP 66.99
1

Fundamentals of Systems Biology From Synthetic Circuits to Whole-cell Models

Fundamentals of Systems Biology From Synthetic Circuits to Whole-cell Models

For decades biology has focused on decoding cellular processes one gene at a time but many of the most pressing biological questions as well as diseases such as cancer and heart disease are related to complex systems involving the interaction of hundreds or even thousands of gene products and other factors. How do we begin to understand this complexity? Fundamentals of Systems Biology: From Synthetic Circuits to Whole-cell Models introduces students to methods they can use to tackle complex systems head-on carefully walking them through studies that comprise the foundation and frontier of systems biology. The first section of the book focuses on bringing students quickly up to speed with a variety of modeling methods in the context of a synthetic biological circuit. This innovative approach builds intuition about the strengths and weaknesses of each method and becomes critical in the book‘s second half where much more complicated network models are addressed including transcriptional signaling metabolic and even integrated multi-network models. The approach makes the work much more accessible to novices (undergraduates medical students and biologists new to mathematical modeling) while still having much to offer experienced modelers-whether their interests are microbes organs whole organisms diseases synthetic biology or just about any field that investigates living systems. | Fundamentals of Systems Biology From Synthetic Circuits to Whole-cell Models

GBP 180.00
1

Cancer Systems Biology

Cancer Systems Biology

The unprecedented amount of data produced with high-throughput experimentation forces biologists to employ mathematical representation and computation methods to glean meaningful information in systems-level biology. Applying this approach to the underlying molecular mechanisms of tumorigenesis cancer researchers can uncover a series of new discoveries and biological insights. The First Cancer Systems Biology Book Designed for Computational and Experimental BiologistsUnusual in its dualistic approach Cancer Systems Biology discusses the recent progress in the understanding of cancer systems biology at a time when more and more researchers and pharmaceutical companies are looking into a systems biology approach to find drugs that can effectively be used to treat cancer patients. Includes Contributions from more than 30 International ExpertsPart I introduces basic concepts and theories of systems biology and their applications in cancer research including case studies of current efforts in cancer systems biology. Part II discusses basic cancer biology and cutting-edge topics of cancer research for computational biologists. In contains an overview of genomics cell signaling and tumorigenesis in addition to hot topics like molecular mechanisms of cancer metastasis and the molecular relationships between solid tumors their microenvironments and tumor blood vessels. Rounding out the book’s solid coverage Part III explores a variety of computational tools and public data resources that are useful for studying cancer problems at a systems level. Cancer systems biology is still in its infancy as a field of study but it is fast becoming indispensable in the battle to defeat cancer and develop successful new treatments. Cancer Systems Biology marks an important step toward reaching that goal.

GBP 69.99
1

Synthetic Biology Handbook

Synthetic Biology Handbook

The Synthetic Biology Handbook explains the major goals of the field of synthetic biology and presents the technical details of the latest advances made in achieving those goals. Offering a comprehensive overview of the current areas of focus in synthetic biology this handbook:Explores the standardisation of classic molecular bioscience approachesAddresses the societal context and potential impacts of synthetic biologyDiscusses the use of legacy systems as tools for new product developmentExamines the design and construction of de novo cells and genetic codesDescribes computational methods for designing genes and gene networksThus the Synthetic Biology Handbook provides an accurate sense of the scope of synthetic biology today. The handbook also affords readers with an opportunity to scrutinize the underlying science and decide for themselves what aspects of synthetic biology are most valuable to their research and practice.

GBP 56.99
1

Advanced Mammalian Cell Culture Techniques Principles and Practices

Advanced Mammalian Cell Culture Techniques Principles and Practices

This up-to-date book compiles both basic and advanced laboratory techniques of mammalian cell culture. It is divided into four major sections encompassing the basics of cell culture nucleic acid and protein isolation cell-staining techniques and cell transfection and single-cell analysis. The topics include aseptic handling media preparation and passaging of cells. The book also outlines downstream assays such as nucleic acid and protein isolation from in-vitro cell cultures. Key Features: Covers cellular staining using fluorescent dyes genetic manipulation of cells via transfection and an introduction to single-cell analyses Discusses basics in cell culture and downstream applications including gene and protein expression analysis Includes the principles underlying each of the techniques and provides a detailed methodology to practice Explores the whole range of techniques – from basic to downstream applications and advanced methods The book is essential for students and researchers in the field of life sciences biotechnology genetics and molecular biology. | Advanced Mammalian Cell Culture Techniques Principles and Practices

GBP 89.99
1

Quantitative Biology From Molecular to Cellular Systems

Quantitative Biology From Molecular to Cellular Systems

Quantitative methods are revolutionizing modern molecular and cellular biology. Groundbreaking technical advances are fueling the rapid expansion in our ability to observe as seen in multidisciplinary studies that integrate theory computation experimental assays and the control of microenvironments. Integrating new experimental and theoretical methods Quantitative Biology: From Molecular to Cellular Systems gives both new and established researchers a solid foundation for starting work in this field. The book is organized into three sections:Fundamental Concepts covers bold ideas that inspire novel approaches in modern quantitative biology. It offers perspectives on evolutionary dynamics system design principles chance and memory and information processing in biology. Methods describes recently developed or improved techniques that are transforming biological research. It covers experimental methods for studying single-molecule biochemistry small-angle scattering from biomolecules subcellular localization of proteins and single-cell behavior. It also describes theoretical methods for synthetic biology and modeling random variations among cells. Molecular and Cellular Systems focuses on specific biological systems where modern quantitative biology methods are making an impact. It incorporates case studies of biological systems for which new concepts or methods are increasing our understanding. Examples include protein kinase at the molecular level the genetic switch of phage lambda at the regulatory system level and Escherichia coli chemotaxis at the cellular level. In short Quantitative Biology presents practical tools for the observation modeling design and manipulation of biological systems from the molecular to the cellular levels. | Quantitative Biology From Molecular to Cellular Systems

GBP 51.99
1

Forensic Biology

Forensic Biology

Over the last several years new research and developments in analysis methods and practice have led to rapid advancements in forensic biology. Identifying critical points of knowledge and new methodological approaches in the field Forensic Biology Second Edition focuses on forensic serology and forensic DNA analysis. It provides students and professionals with a scientific grounding in biological evidence—both the techniques used to identify it and the methodology to analyze it. This second edition:Introduces the language of forensic biology enabling students to become comfortable with usage and terminologyProvides clear explanations of the principles of forensic identification and analysis of biological evidenceExplains forensic serology and DNA techniques used in the field and the laboratoryDiscusses the benefits and limitations that apply to various forensic biology techniquesIncludes schematic illustrations to clarify conceptsPresents three new chapters created for this edition Adds more than two hundred new color figures Covering the full scope of forensic biology the book uses an accessible straightforward style designed to enhance students’ education and training so they are prepared both in the laboratory and in the field.

GBP 66.99
1

Human Biology and History

Human Biology and History

The biology of people in the past is a rapidly expanding field of historical study. Our capacity to understand the biology of historical populations is experiencing remarkable developments on both theoretical and analytical fronts. Human Biology and History weaves together the fields of biology archaeology and anthropology in an exchange of methods and theoretical perspectives that exemplify the interaction between human biology and history. The book presents methods developed for the analysis of biological material that can be applied to historical specimens to reveal the lifestyles and environments of individuals who lived thousands of years ago. Historical data sources are used to reveal the biology and population structure of past civilizations while biological methods are used to interpret historical patterns and processes. This multi-disciplinary volume presents a unique interlacing of human biology and history to illustrate how individuals and societies have evolved over time. It is an insightful reference for human biologists historians and students interested in the intriguing connections that can be made when scientific techniques are applied within a historical context.

GBP 56.99
1

Biology of Fishes

Biology of Fishes

The Third Edition of Biology of Fishes is chiefly about fish as remarkably efficient machines for coping with the many problems that life in water entails and looks at many such special cases. Fishes form the largest group of vertebrates with around 20 000 known species and they display a remarkable diversity of size shape internal structure and ecology to cope with environments ranging from transient puddles to the abyssal depths of the sea. Biology of Fishes does not try to cover all aspects of fish biology but focuses on the ingenious ways in which fish have resolved the particular problems that come from living in water especially body fluid regulation locomotion feeding mechanisms and sensory systems. Enough detail is provided for the reader to be able to go on and use primary research papers. Each chapter has been thoroughly updated and a new chapter on the immune system has been added. This is an ideal textbook for students of fish biology and any of the branches of aquatic biology. Given its skilful combination of breadth and detail the book also provides a manageable review of fish biology for experienced biologists.

GBP 180.00
1

Prion Biology Research and Advances

Prion Biology Research and Advances

This title includes a number of Open Access chapters. This book contains a selection of chapters aimed to provide a better understanding prion structure and biology. Together these chapters provide an overview of prion biology and underscore some of the challenges we face if we want to understand how this lively pathogen propagates and evolves in mammals. There is also mounting evidence that studying prion biology has a wider relevance due to similarities in the processes of protein misfolding and aggregation between prion disorders and other neurodegenerative disorders such as Alzheimer’s Parkinson’s and Huntington’s diseases. | Prion Biology Research and Advances

GBP 82.99
1

Reproductive Biology and Phylogeny of Lizards and Tuatara

Reproductive Biology and Phylogeny of Lizards and Tuatara

Reproductive Biology and Phylogeny of Lizards and Tuatara is a remarkable compendium of chapters written by the world's leading experts from over four continents. The book begins with a chapter recounting historical discoveries in reproductive biology and a review of phylogenetics and up-to-date hypotheses concerning evolutionary relationships among lizards. Following these chapters are detailed reviews with additional new data concerning chemical communication sexual selection reproductive cues female reproductive anatomy female reproductive cycles oogenesis parthenogenesis male reproductive anatomy male reproductive cycles spermatogenesis reproductive investment viviparity and placentation multiple paternity and parental care. The book culminates in two chapters on tuatara reproduction giving unique insight into evolutionary patterns in reproductive biology in squamates and tuatara. This is an essential resource for anyone studying reproduction in reptiles and/or vertebrates and offers a fascinating read for those interested in reproductive biology.

GBP 44.99
1

Molecular Biology Structure and Dynamics of Genomes and Proteomes

Molecular Biology Structure and Dynamics of Genomes and Proteomes

Molecular Biology: Structure and Dynamics of Genomes and Proteomes second edition illustrates the essential principles behind the transmission and expression of genetic information at the level of DNA RNA and proteins. Emphasis is on the experimental basis of discovery and the most recent advances in the field while presenting a rigorous yet still concise summary of the structural mechanisms of molecular biology. Topics new to this edition include the CRISPR-Cas gene editing system Coronaviruses – structure genome vaccine and drug development and newly recognized mechanisms for transcription termination. The text is written for advanced undergraduate or graduate-level courses in molecular biology. Key Features Highlights the experimental basis of important discoveries in molecular biology Thoroughly updated with new information on gene editing tools viruses and transcription mechanisms termination and antisense Provides learning objectives for each chapter Includes a list of relevant videos from the Internet about the topics covered in the chapter | Molecular Biology Structure and Dynamics of Genomes and Proteomes

GBP 64.99
1

Cells in Evolutionary Biology Translating Genotypes into Phenotypes - Past Present Future

Cells in Evolutionary Biology Translating Genotypes into Phenotypes - Past Present Future

This book is the first in a projected series on Evolutionary Cell Biology the intent of which is to demonstrate the essential role of cellular mechanisms in transforming the genotype into the phenotype by transforming gene activity into evolutionary change in morphology. This book —Cells in Evolutionary Biology — evaluates the evolution of cells themselves and the role cells have been viewed to play as agents of change at other levels of biological organization. Chapters explore Darwin’s use of cells in his theory of evolution and how Weismann’s theory of the separation of germ plasm from body cells brought cells to center stage in understanding how acquired changes to cells within generations are not passed on to future generations. Chapter 7 of this book is freely available as a downloadable Open Access PDF under a Creative Commons Attribution-Non Commercial-No Derivatives 3. 0 license. https://s3-us-west-2. amazonaws. com/tandfbis/rt-files/docs/Open+Access+Chapters/9781315155968_oachapter7. pdf | Cells in Evolutionary Biology Translating Genotypes into Phenotypes - Past Present Future

GBP 46.99
1

Helicobacter pylori Biology and Clinical Practice

Helicobacter pylori Biology and Clinical Practice

Helicobacter pylori: Biology and Clinical Practice is the first book to fully describe H. pylori and the pathogenesis of H. pylori infections. It delineates the genome of H. pylori discusses the molecular biology of the unique urease enzyme and examines the clinical application of these discoveries. The book describes the epidemiology of H. pylori and its relevance to gastric cancer and it offers clear guidance to clinicians for the diagnosis and treatment of peptic ulcer and non-ulcer dyspepsia in adults and children. Vaccine principles and possibilities are presented for the first time. Edited by the leader of the microbiology team that achieved the first culture of H. pylori and named the Helicobacter genus this book is essential for bacteriologists gastroenterologists microbiologists infectious disease specialists and other researchers interested in H. pylori. | Helicobacter pylori Biology and Clinical Practice

GBP 240.00
1

Radiation in Medicine and Biology

Radiation in Medicine and Biology

This book focuses on the conventional and emerging applications of radiations which include radio waves and ultraviolet and gamma radiations. It discusses new techniques in radiation therapy and the effects of ionizing radiations on biological systems. The applications of radiations in the synthesis and use of nanoparticles along with the effects of hypergravity indicate a new trend. The book offers a concise account of the latest studies carried out so far and shows the new initiatives to be undertaken in the field of medicine and biology. It covers the medical use of radiations such as ferrous sulfate–benzoic acid–xylenol orange dosimetry Co-60 tomotherapy radio-electro-chemotherapy and fractional radiotherapy and radiobiological effects such as the effects of cell phone radiations on human health parameters and the combined effects of radiations and hypergravity on plants. | Radiation in Medicine and Biology

GBP 95.00
1

Pollen Biology and Biotechnology

Pollen Biology and Biotechnology

The author offers an overview of pollen biology and biotechnology for students and researchers in areas such as reproductive biology biotechnology aeropalynology plant breeding horticulture and forestry. Citing more than 1 500 references to pollen research the text covers topics including advances in understanding pollen tube growth the use of pollen for gene transfer and advantages and disadvantages of various pollination systems for production of species limits.

GBP 170.00
1